Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain. Li X,Zhuo W,Yu J. et al. Acta Crystallographica Section D Biological Crystallography . 2013Li, X., Zhuo, W., Yu, J., Ge, J., Gu, J., Feng, Y., Yang, M...
Like all ABC transporters, BceAB-type transporters are composed of a nucleotide-binding domain (NBD) and a transmembrane domain (TMD). The NBD hydrolyses ATP, which drives conformational changes in the TMD, leading to substrate translocation. The TMD of BceAB-type ABC transporters are characterize...
Mutations in the nucleotide binding domain of the alpha subunits of the F1-ATPase from thermophilic Bacillus PS3 that affect cross-talk between nucleotide ... Dou, W.S. Allison, Mutations in the nucleotide binding domain of the α subunits of the F1-ATPase from thermophilic bacillus PS3 that...
The C1’ atoms of every nucleotide in one nucleosome, pictured as the bottom nucleosome of each graph in Fig. 1b, were used to align each frame of the trajectory. The dyad and opposing points in the other nucleosome, pictured as the top nucleosome of each graph in Fig. 1b, were ...
NLRC4:英文全称为Nucleotide-binding oligomerization domain, leucine-rich repeat and caspase recruitment domain-containing 4,即核苷酸结合寡聚结构域,富含亮氨酸重复序列和含caspase募集结构域-4,一种炎症小体支架蛋白(scaffold protein),与炎症小体感受器(NLR家族凋亡抑制蛋白(NAIP))结合时寡聚化,并形成活化caspase...
Nucleotide-binding-oligomerization domain-mediated signaling may also control toll-like receptor-induced proinflammatory pathways. SUMMARY: Intersections between toll-like receptor and nucleotide-binding-oligomerization domain pathways may exist to refine the host immune response to pathogens and prevent ...
Crystal structure of the nucleotide-binding domain of the ABC-transporter haemolysin B. Identification of a variable region within ABC helical domains J. Mol. Biol., 330 (2003), pp. 333-342 View PDFView articleView in ScopusGoogle Scholar 33 G. Verdon, S.V. Albers, B.W. Dijkstra, A.J...
Alignment of these regions on the known structure of HIV-1 reverse transcriptase allowed us to predict the position of the downstream nucleotide binding site in the conserved ''fingers'' subdomain present near the active site cleft of both RNA and DNA polymerases. The N-terminal nucleotide ...
Deletion of the amino-terminal transmembrane domain of SRβ did not affect receptor dimerization, but revealed a cryptic translocation signal that overlaps the GTPase domain. We demonstrate that the domain of SRα that binds SRβ does so by binding directly to the nucleotide-bound form of the ...
(ii) ADP is unable to induce conformational changes of ABCE1 required for ribosome binding4,5. Notwithstanding, taking a two-step mechanism with two distinct nucleotide-binding events into account, AMP-PNP prevents the second step, the splitting process, because ABCE1 is trapped in the first ...