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Of note, the AGS of complete prokaryotic genomes increases with the cumulative number of associated phages and other mobile genetic elements37. Similarly, AGS estimates derived from metagenomic sequences of uncultured “free-living” microbes (captured in 0.1–3 µm-size filters) may also be...
The inherent redundancy of the genetic code allows the same amino acid to be specified by one to six different codons so that there are, in principle, a vast amount of nucleic acid sequences to describe the primary structure of a given protein2. Coding DNA sequences can therefore carry ...
Nebulization creates shear force with compressed gas, forcing a nucleic acid solution through a small hole in a nebulizer. The aerosolized sample with fragmented DNA is then collected. The level of fragmentation can be controll...
This archive contains the fastq sequences, de novo assembly, and binning results. A copy of data has also been deposited into the Genome Sequence Archive (GSA) with submission number HRA004617. The metagenomic data of Yang et al. can be found by PRJNA763023.Code availability No unique ...
For example, AGT encodes the amino acid serine. The dictionary of DNA letters that make up the amino acids is called the genetic code4. There are 64 different triplets or codons, 61 of which encode an amino acid (different triplets can encode the same amino acid), and three of which ...
Reutilization of both hypoxanthine and xanthine for nucleotide and nucleic acid synthesis is markedly enhanced when their oxidations are inhibited by allopurinol and oxipurinol. This reutilization does not disrupt normal nucleic acid anabolism, however, because feedback inhibition is an integral part of ...
Which of the following is false about DNA? (a) It is formed in a helix form (b) It contains genetic material (c) It runs parallel (d) There is a phosphate group, sugar, and nucleic acid backbone. Consider the strand in a DNA double-he...
In total, our alignment contains 523,035 amino acid positions. We inferred phylogenies in IQTree225 using maximum likelihood for the nucleotide position two and amino acid alignments, respectively, as well as with ASTRAL based on gene trees using maximum likelihood on individual amino acid ...
Here we report that pyrrolysyl-tRNA synthetase (PylRS) and certain PylRS variants accept α-hydroxy, α-thio and N-formyl-l-α-amino acids, as well as α-carboxy acid monomers that are precursors to polyketide natural products. These monomers are accommodated and accepted by the translation ...