The Nitric Oxide (NO) SolutionBill Gottlieb
In conclusion, the nitric oxide/superoxide assay allows the specific, sensitive, and simultaneous detection of NO and O2−2. The simulation model developed also allows the reliable prediction of the reaction between NO and O2−2 as well as their kinetic interaction with other biomolecules. ...
The chemical signalling molecule nitric oxide (NO), which freely diffuses through aqueous and lipid environments, subserves an array of functions in the mammalian central nervous system, such as the regulation of synaptic plasticity, blood flow and neurohormone secretion. In this Review, we consider...
primary and secondary metabolisms27, and the elevated expression in the COM nitrifier can relieve the toxicity of accumulated NO2-in the plastisphere28. Importantly, we found that EPS synthesis, purine metabolism and quorum sensing (i.e., cGMP/cAMP signaling) pathways were robustly expressed in ...
Nitric oxide: a one‐trick pony? This issue, pp 1340–2. Summary Background: The nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) signaling cascade is involved in the precise regulation of platelet responses. NO released from the endothelium is known to activate NO‐sensitive guanylyl ...
(Figs.1and2). Notably, nitric oxide (NO) reductase transcripts (norBD) were detected inNitrosospira(MAG397) andNitrosomonas(MAG876), but not in the COM nitrifierNitrospira_defluvii(MAG262) (Supplementary Fig.15). This absence suggests an inability of the COM nitrifier to generate N2O via ...
Another mechanism through which tobacco smoke can impair BBB viability is through the alteration of nitric oxide bioavailability. NO is a molecular mediator involved in a variety of physiologic and pathological processes. Three isoforms of NOS have been described: neuronal NOS (nNOS), endothelial (eNO...
Nitric oxide (NO) is recognized as an endogenous signaling molecule that plays an important role in the defence responses of medicinal plants to NaCl stres
The presently disclosed subject matter relates to nitric oxide-releasing particles for delivering nitric oxide, and their use in biomedical and pharmaceutical applications.
Mitchell et al., "Cellular Glutathione by Diethyl Meleate of Buthionine Sulfoximine: No Effect of Glutathione Depletion on the Oxygen Enhancement Ratio," Radiation Research, 96, 422-428 (1983). Mitchell et al., "Radiation Sensitisation by Nitric Oxide Releasing Agents," British Journal of Cancer...