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Mitosis relies on forces generated in the spindle, a micro-machine composed of microtubules and associated proteins. Forces are required for the congression of chromosomes to the metaphase plate and their separation in anaphase. However, besides forces,
mitotic spindlemicrotubuleschiralitytorquekinesin-5Mitosis relies on forces generated in the spindle, a micro- machine composed of microtubules and associated proteins. Forces are required for the congression of chromosomes to the metaphase plate and their separation in anaphase. However, besides forces,...
The mitotic spindle: a complex and dynamic intracellular machine. Diego Rivera's 1934 mural, Man at the Crossroads, depicts the great challenges and possibilities of the 20th century. Jutting from the center is a disembod... DJ Sharp - 《Methods A Companion to Methods in Enzymology》 被引量...
spindle fiber (redirected frommitotic spindle) Thesaurus Medical Encyclopedia Related to mitotic spindle:cell cycle,Mitotic apparatus,Spindle apparatus,Spindle fibers n. One of a network of achromatic filaments that extend inward from the poles of a dividing cell, forming a spindle-shaped figure. ...
Concentrating on the mitotic spindle. In eukaryotes, the microtubule-based spindle drives chromosome segregation. In this issue, Schweizer et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/... Paul,S,Maddox,... - 《Journal of Cell Biology》 被引量: 0发表: 2015年 Ovarian spindle ...
In which phase of cell division is marked by the dissolution of the nuclear membrane, the condensation of chromosomes, and the formation of the mitotic spindle? a. prophase b. metaphase c. telophase d. anaphase Describe what happens to the chromosomes at each phase o...
Microtubule-associated motor proteins are thought to be involved in spindle formation and chromosome movements in mitosis/meiosis. We have molecularly cloned cDNAs for a gene that codes for a novel member of the kinesin family of proteins. Nucleotide sequencing reveals that the predicted gene product...
In this study, we demonstrate the role of two Wnt signaling pathways involved in regulating the mitotic spindle. First, the nontranscriptional Wnt spindle alignment pathway requires contact from the C blastomere to align the spindle of ABar. We show that the three Dshs differentially participate ...
The mitotic spindle assembly checkpoint (SAC) is an essential control system of the eukaryotic cell cycle. This surveillance mechanism monitors the kinetoc... Bolanos-Garcia,M Victor - 《Current Cancer Drug Targets》 被引量: 37发表: 2009年 Stable kinetochore–microtubule attachment is sufficient to...