Separation of duplicated spindle poles is the first step in forming the mitotic spindle. Kinesin-5 crosslinks and slides anti-parallel microtubules, but it is udoi:10.2139/ssrn.3316803Leary, AllenNazarova, ElenaSim, ShannonShulist, Kristy
Micromanipulation of Chromosomes and the Mitotic Spindle Using Laser Microsurgery (Laser Scissors) and Laser-Induced Optical Forces (Laser Tweezers) Individual chromosomes in living cells can be manipulated by optical scissors and optical tweezers. In addition to the selective manipulation of chromosomes fo...
To facilitate faithful chromosome segregation during mitosis, the kinetochore is assembled on centromere DNA to form a dynamic interface with microtubules from the mitotic spindle (Cheeseman and Desai, 2008, Santaguida and Musacchio, 2009). To establish a functional kinetochore structure, a subset of...
Mitotic segregation of chromosomes requires spindle pole functions for microtubule nucleation, minus end organization, and regulation of dynamics. gamma-Tu... J L,Paluh,Nogales,... - 《Molecular Biology of the Cell》 被引量: 250发表: 2000年 Gamma-tubulin complexes and their interaction with micr...
The chromatids detach from one another during: a. anaphase b. metaphase c. interphase d. prophase e. telophase The mitotic spindle disassembles in ___: A. Prophase B. Metaphase C. Anaphase D. Telophase The chromosomes are aligned at the spindle equator during a) ana...
XRCC8 mutations did not result in a delay of mitotic entry when exposed to PARP inhibitors, in contrast to BRCA2 mutations that did exhibit a delayed mitotic entry. Prior reports have identified an ATM gene mutation in XRCC8 mutant cell lines. XRCC8 mutants displayed a maximum level of ...
Mitotic arrest deficient 2 (MAD2) is an essential component of the mitotic spindle checkpoint pathway. It was previously shown to be associated with drug r... Y Du,Y Fang,C Liu,... - 《Biochemical & Biophysical Research Communications》 被引量: 80发表: 2006年 Appoptosin is a Novel Pro...
mitotic figures. Large numbers of macrophages and mature lymphocytes were admixed with the neoplastic cells. OPA containing MGs were poorly cellular and composed of spindle, stellate and elongated cells with round to oval nuclei, and inserted in a pale blue slightly vacuolar extracellular myxoid ...
The group administered 100% concentrated sample water for 30 days exhibited a marked (p < 0.005*, p < 0.001**, p < 0.0001***) reduction in the mitotic index. properties of biological processes The groups treated with 10% and 100% sample concentrations for extended periods displayed a ...
Cleveland, CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint, Nat. Cell Biol. 2 (2000) 484-491.Xue biao yao,Ariane Abrieu,Yun Zheng,et al.CENP-E forms a link between attachment of spindle microtubules to kinetochoms and the mitotic ...