The Microbiota-gut-brain axis: Clinical Applications In Obesity and Type 2 Diabetesdoi:10.24875/RIC.22000197Moser, BrandyMilligan, Megan A.Dao, Maria C.Clinical & Translational Investigation / Revista de Investigación Clínica
Here we show in Drosophila that a microbiome–gut–brain axis detects a deficit of EAAs and stimulates a compensatory appetite for EAAs. We found that the neuropeptide CNMamide (CNMa)5 was highly induced in enterocytes of the anterior midgut during protein deprivation. Silencing of the CNMa–...
The gut-microbiota-brain axis (GUMBA) is a bidirectional communication between the GM and the brain with multiple routes and mechanisms, including neural, endocrine, and immune pathways [4,5]. In humans, the neural pathway consists of the vagus nerve that plays both afferent and efferent roles ...
Crosstalk between the gut microbiota and the host has attracted considerable attention owing to its involvement in diverse diseases. Chronic kidney disease (CKD) is commonly associated with hypertension and is characterized by immune dysregulation, metab
Are brain disorders potentially shaped by the gut microbiota [15]? What role does diet play and what is its scope in influencing the microbiota–gut–brain axis [16, 17]? How do dietary supplements exert their apparent effect(s) on stress, mood, and cognition [18, 19]? What physiological...
Obesity is worldwide epidemic given its rapid growth in global prevalence. Among the risk factors contributing to obesity, human gut microbiome recently emerges with unprecedented intimacy in host metabolism and inflammation. With the advances in sequencing technology, more and more detailed understanding...
Furthermore, advanced mapping of the human microbiome is required to investigate the metabolic implications of the gut-brain axis to develop targeted interventions for obesity and metabolic syndrome. 展开 关键词: Keywords microbiome metabolic syndrome gut-brain axis ...
This interaction, termed the gut-brain axis (also known as the brain-gut axis), is thought to be involved in many regular functions and systems within the healthy body, in addition to the pathogenesis of many diseases from neurological and degenerative conditions to autoimmune diseases. The gut...
Increasing epidemiological evidence shows that the use of cannabis during adolescence could increase the risk for psychosis in adulthood. However, the precise mechanisms underlying long-lasting cannabis-induced risk for psychosis remain unclear. Accumulating evidence suggests the role of gut microbiota in ...
Conversely, signals from the brain can influence the composition and function of the gut microbiota. This bidirectional communication across the gut microbiota–brain axis, involving multiple biochemical and cellular mediators, is recognized as a major brain–body network that integrates cues from the ...