16 We review the gut microbiota as a key regulator of host metabolism, central appetite, and food reward, and its role in metabolic disorders such as obesity, summarise the literature on potential mechanisms of gut–brain axis signalling, review how some bacterial strains might contribute to, or...
The Microbiota-gut-brain axis: Clinical Applications In Obesity and Type 2 Diabetesdoi:10.24875/RIC.22000197Moser, BrandyMilligan, Megan A.Dao, Maria C.Clinical & Translational Investigation / Revista de Investigación Clínica
Here we show in Drosophila that a microbiome–gut–brain axis detects a deficit of EAAs and stimulates a compensatory appetite for EAAs. We found that the neuropeptide CNMamide (CNMa)5 was highly induced in enterocytes of the anterior midgut during protein deprivation. Silencing of the CNMa–...
Crosstalk between the gut microbiota and the host has attracted considerable attention owing to its involvement in diverse diseases. Chronic kidney disease (CKD) is commonly associated with hypertension and is characterized by immune dysregulation, metab
Leucine-Restricted Diet Ameliorates Obesity-Linked Cognitive Deficits: Involvement of the Microbiota–Gut–Brain Axis Leucine restriction (LR) improves insulin resistance and promotes white adipose tissue browning. However, the effect of LR on obesity-associated cognitive ... D Wang,L Wang,L Han,.....
Mechanisms of traditional Chinese medicines in improving metabolic diseases by regulating the gut microbiota mainly includes the modulation of intestinal barrier function, metabolic endotoxemia, inflammation, short-chain fatty acids, gut-brain axis, and bile-acid metabolism. Download: Download high-res imag...
Obesity is worldwide epidemic given its rapid growth in global prevalence. Among the risk factors contributing to obesity, human gut microbiome recently emerges with unprecedented intimacy in host metabolism and inflammation. With the advances in sequencing technology, more and more detailed understanding...
738 INDEPENDENT EFFECTS OF RACE AND DIET ON THE BRAIN-GUT MICROBIOME AXIS IN OBESITY The bidirectional communication between brain structures and the gastrointestinal tract involving the microbiota defines the scientific concept of the brai... M Guan,TS Dong,EA Mayer,... - 《Gastroenterology》 被引...
The gut microbiota is vital to human health10,11. Notably, the brain-gut axis has been intensively studied in the past few years12,13,14. Prior studies have reported that the gut microbiota exhibits circadian rhythms, which interact with host circadian rhythms15,16,17. Sleep disturbances, such...
The microbiota–gut–brain axis plays an important role in the development of depression. The aim of this study was to investigate the effects of 5-HT on cognitive function, learning and memory induced by chroni... Junxing Ma, Ran Wang, Yaoxing Chen, Zixu Wang and Yulan Dong ...