homeostasisspecies.governedChanges in the composition of the gut microbiota are associated with many human diseases.So far,however,we have failed to define homeostasis or dysbiosis by the presence or absence of specific microbial species.The composition and function of the adult gut microbiota is gover...
Work on the biology of the gut–liver axis has assisted in understanding the basic biology of both alcoholic fatty liver disease and nonalcoholic fatty liver disease (NAFLD). Of immense importance is the advancement in understanding the role of the microbiome, driven by high-throughput DNA ...
Gut homeostasis, including intestinal immunity and microbiome, is essential for cognitive function via the gut-brain axis. This axis is altered in high-fat diet (HFD)-induced cognitive impairment and is closel... Wei Pan, Jinxiu Zhao, Jiacheng Wu, Daxiang Xu, Xianran Meng, Pengfei Jiang, ...
different body sites. In this review, we describe the key steps of the co-evolution betweenHomo sapiensand microbiome and how this adaptation can impact on immunosenescence and inflammaging. We briefly summarized the role of gut microbiota in aging and longevity while bringing out the involvement of...
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Establishing or exaggerating causality for the gut microbiome: lessons from human microbiota-associated rodents. Cell 180, 221–232 (2020). Article CAS PubMed Google Scholar Caporaso, J. G. et al. Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms. ...
In-depth understanding of the underlying mechanisms that control homeostasis and dysbiosis of the gut microbiota represents an important step in our ability to reliably modulate the gut microbiota with positive clinical outcomes. The potential of microbiome-based therapeutics to treat epidemic human ...
a gut–liver axis involving intestinal microbiome and autoimmune liver diseases will be elucidated separately, given the special anatomic and physiological relationships of liver, intestine and its microbial contents. We will not discuss the bacterial species observed in other sites, such as the skin ...
et al. The lung microbiome in idiopathic pulmonary fibrosis: a promising approach for targeted therapies. Int. J. Mol. Sci. 18, E2735 (2017). Article PubMed CAS Google Scholar Matsuoka, K. & Kanai, T. The gut microbiota and inflammatory bowel disease. Semin. Immunopathol. 37, 47–55 ...
The gut microbiome exerts a considerable influence on human neurophysiology and mental health. Interactions between intestinal microbiology and host regulatory systems have now been implicated both in the development of psychiatric conditions and in the