white blood cells, and platelets. Bone marrow stem cells play an important role in immunity as they generate lymphocytes. While some white blood cells mature in bone marrow, certain types of lymphocytes migrate to lymphatic organs, such as ...
we attempted to determine the structures of Lola29F and Lola29M and the mechanism whereby these two isoforms are produced in a sex-dependent manner. We presumed that Lola29F might be a proteolytic product of Lola29M. To test this idea, we overexpressed alola29mgene decorated with...
MHC II-restricted CD4+ T cells that are responsive to microbial antigens are a major immune cell population in the intestine and were shown to play key roles in both homeostasis and chronic inflammation4. Considerable efforts have been made in the past to unravel how interactions with intestinal...
LTBR blockade for eight weeks reduced B-cell accumulation (approximately 5-fold), eliminated HEV in lacrimal glands, and reduced the entry rate of lymphocytes into lacrimal glands. Affymetrix-chip analysis revealed numerous changes in mRNA expression due to LTBR blockade, including reduction of homeo...
To examine the process of genome reduction after the loss of a major metabolic function, we have completely sequenced the genome of the non-photosynthetic plastid of Helicosporidium sp., a parasitic green alga. Helicosporidia are obligate parasites of invertebrates with a unique morphology and infe...
Then, lymphocytes are transported to the tumor site to exert an immune response [16, 17, 19, 20, 22, 56,57,58,59], and an internal cancer-immunity cycle may be formed in these tissues. However, the initiation and process of its formation is still unclear. We found by transcriptome ...
Erdheim-Chester Disease (ECD) is a rare form of non Langerhans' cell histiocytosis. Individuals affected by this disease are typically adults between their 5th and 7th decades of life. Males and females are almost equally affected. The multi systemic for
the system of glands, tissues, and passages involved in generating lymphocytes and circulating them through the body in the medium of lymph: includes the lymph vessels, lymph nodes, thymus, and spleen. [1820–30] Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd....
of the myeloid lineage where latent genome is found in monocytes and their CD34+haemopoietic progenitors2,3,4,5,6. Despite the fact that haemopoietic cell types derive from CD34+progenitor cells, HCMV is only detectable in the myeloid cells of the peripheral blood and not lymphocytes7. This ...
Leukocytes are the major effectors of inflammatory damage in stroke brains. Among them, neutrophils and macrophages are early responders to a stroke. To investigate whether BR therapy affects central nervous system (CNS) inflammatory infiltration, we designed a study to analyze leukocyte invasion in th...