The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastomaGlioblastoma, Methuosis, Cell death, Chalcones, C-Jun N-terminal kinase, Vacuoles, EndosomesBackgroundSynthetic indolyl- pyridinyl- propenones (IPPs) induce methuosis, a form of non...
As a well-known pathway participating in cellular activities, the JNK signaling pathway is involved in both apoptosis and cancer cell survival. For example, JNK mediates the compensatory cell proliferation in tumors. Nevertheless, via regulating the fos gene and pro-apoptotic hid gene, the JAK/...
The JNK Signaling Pathway Edited by Anning Lin (University of Chicago). Landes Bioscience, Georgetown, TX. 2006. x + 97 pp. 6 × 9.5 in. $129.00. ISBN 1-58706-120-1. None - 《Journal of Natural Products》 被引量: 0发表: 2006年 The JNK Signaling Pathway A Lin 被引量: 4发表: 20...
In T cells, MIF-mediated activation of the JNK pathway led to upregulated gene expression of the inflammatory chemokine CXCL8. Activation of JNK signalling by MIF involved the upstream kinases PI3K and SRC and was found to be dependent on CXCR4 and CD74. Together, these data show that the...
JNK Signaling JNK activation is required for apoptosis but c-jun, a protein in the JNK signaling pathway, is not always required. Search [A Case of Cancerous Transformation involving Formerly Identified Posted onDecember 14, 2024 Reply The main responsible particles (the amanitins) are bicyclic ...
Morishige N, Nishida T and Sonoda KH: Role of the JNK signaling pathway in downregulation of connexin43 by TNF‑α in human corneal fibroblasts... Kimura,Kazuhiro,Orita,... - 《Current Eye Research》 被引量: 34发表: 2013年 Role of the JNK signaling pathway in downregulation of connexin43...
The purpose of this review is to summarize recent advances that have been made toward understanding the JNK signaling pathway. It is now known that JNK is required for embryonic morphogenesis and that this signaling pathway contributes to the regulation of cell proliferation and apoptosis. JNK also...
Results Evidence for a role of the JNK/c-Jun/AP-1 pathway in gal-1-induced cell death. Jurkat T lymphocytes exposed to gal-1 for 6 h underwent apoptosis as indicated by DNA fragmentation (Figure 1). To elucidate the role of JNK and AP-1 for gal-1 induced death, we preincubated ...
Inhibition of T cell antigen receptor signaling by VHX, a new dual-specificity phosphatase related to VHR Shen Y, Luche R, Wei B, Gordon ML, Diltz CD, Tonks NK (2001) Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1. ... A Alonso,JJ Merlo,S Na,......
Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1. Yu Shen,Ralf Luche,Bo Wei,Marcia L. Gordon,Curtis D. Diltz,Nicholas... Shen,Yu,Luche,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 63发表: 2001年 Myri...