This is known as ‘intentional binding’ and, in healthy adults, depends partly on advance prediction of action outcomes. Notably, this predictive contribution is disrupted in patients with schizophrenia. In the present study we aimed to characterise the psychotomimetic effect of ketamine, a drug ...
Ketamine, a synthetic derivative of phencyclidine, is a commonly misused par ty drug that is restricted in high-income countries because of its addictive potential. Ketamine is also used as an anaesthetic in human and veterinary medicine. In the 1990s, research using ketamine to study the pathophy...
OPEN Molecular Psychiatry (2018) 23, 59–69 www.nature.com/mp REVIEW The effects of ketamine on dopaminergic function: meta-analysis and review of the implications for neuropsychiatric disorders M Kokkinou1,2, AH Ashok1,2,3 and OD Howes1,2,3 Ketamine is a non-competitive antagonist at ...
The effects of ketamine on dopaminergic function: meta-analysis and review of the implications for neuropsychiatric disorders. Mol Psychiatry 2018; 23: 59-69.Kokkinou M, Ashok AH, Howes OD (2018) The effects of ketamine on dopaminergic function: meta-analysis and review of the implications for...
The involvement of the endocannabinoid system in the peripheral antinociceptive action of ketamine. J. Pain 19, 487–495 (2017). Article CAS PubMed Google Scholar Petrosino, S. & Di Marzo, V. The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of ...
The implications of diversity in the subunit composition of GIRK channels has not been fully explored, but it might give the channel distinctive functional properties, such as differences in opening time, which seems to be longer for heterotetrameric channels than homotetramers (Aguado et al., 20...
with the new improved Frequency Extended Method and with the traditional ActiGraph method for comparison. A high-resolution PA intensity spectrum was investigated as well as traditional crude PA intensity categories. Children treated for aortic stenosis had a pattern of less PA in the highest ...
In fact, gabapentin may exert a selective effect on the nociceptive process involved in central neuronal sensitization, which is the rationale for its use in the treatment of acute postoperative pain [62]. In addition, ketamine is an NMDA-receptor antagonist that has been demonstrated to prevent ...
KETAMINE REDUCES CELL DEATH IN RAT BRAIN 285 Figure 2. (A) Pictograms of differences in cell death from control group, at 1 h and 4 h following 4% formalin injection (blue p Ͻ 0.05, green p Ͻ 0.01, red p Ͻ 0.001). P1 rats: Cell death increased bilaterally at 1 h in the...
Mice were anesthetized by IP injection of a rodent cocktail composed of ketamine (100 mg/kg)/xylazine (10 mg/kg)/acepromazine (3 mg/kg) and their hindlimb was positioned into the field of irradiation of a Multirad225 irradiation machine (Precision X-Ray) and were given a 18 Gy ...