However, due to different methodological approaches, different investigated populations, and varying measurement timepoints, results are not consistent, and the functional significance of the observed brain changes remains a matter of open debate. Inhibition of glutamate release during acute ketamine ...
Ketamine commonly and rapidly induces dissociative and other altered states of consciousness (ASCs) in humans. However, the neural mechanisms that contribute to these experiences remain unknown. We used functional neuroimaging to engage key regions of th
Given the increasing frequency of TKA, understanding the risk factors for poor pain outcomes after this surgery holds great import. This study investigated the influence of sex on the trajectory of acute pain-related outcomes following TKA, in an age-matched cohort of men and women. Despite simil...
Elon Musk has been vocal on his platform “X,” formerly known asTwitter, about his use of ketamine. But, in aninterviewposted Monday with former CNN anchor Don Lemon, Musk delves into the reasons why. “There are times when I have sort of a negative chemical state in my brain,” Musk...
However, these data cannot explain the relief that occurs within minutes of intranasal ketamine delivery. We hypothesize that the ultra-rapid effects of intranasal administration in humans may be due to ketamine blocking the NMDAR circuits that generate the emotional representations of pain (eg, ...
Ketamine produces no detectable long-term positive or negative effects on cognitive flexibility or reinforcement learning of male rats Anthony N. Nist Stephen J. Walsh Timothy A. Shahan Psychopharmacology (2024) Trait sensitivity to positive feedback is a predisposing factor for several aspects of ...
Evaluation of the antipsychotic potential of Panax quinquefolium in ketamine induced experimental psychosis model in mice. In the chronic studies, PQ reduced the ketamine induced enhanced immobility in the forced swim test and did not show extra-pyramidal side effects in bar... M Chatterjee,S Singh...
Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers. Biol Psychiatry. 1998;43(11):811-816.PubMedGoogle Scholar 13. Malhotra AK, Pinals DA, Adler CM, et al. Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic...
Other types of ATSs, such as Magu, a methamphetamine-caffeine mixture, were used by 38.9% of the participants, and Ecstasy was used by 12.4%. The top three frequently used non-ATSs were ketamine (28.6%), cannabis (15.2%), and heroin (8.9%). Table 1 Participant Demographics and ...
A main effect of group was observed in alcohol craving (1, 54=8.4;p=0.005) and anxiety (1, 54=7.02;p=0.01) responses, with the AD group showing higher responses compared to the SD group (p<.01) (seeFigure 2a and b). Interaction effects (group X condition) ...