The Human Protein Atlas(HPA)是一个功能强大且内容丰富的药物靶点、蛋白靶点数据库,为科研人员提供了全面的蛋白质组图谱和相关信息。以下是对HPA的详细介绍: 一、数据库亮点 HPA数据库的亮点在于其十二大版块分类齐全,涵盖了组织、细胞、病理等多个常用版块,使得科研人员能够轻松...
Fig. 1.ITGB6RNA expression in human normal tissue plotted as rates per kilobase million (RPKM). Data were obtained from Human Protein Atlas Dataset available fromproteinatlas.org. 不仅可以直接使用,而且可以独立撑起一个figure。这数据库,我王多余学了。 THE HUMAN PROTEIN ATLAS,简称HPA,分为Cell,Tis...
Human Protein Atlasbioproductiondrug developmentprecision medicineThe Human Protein Atlas (HPA) is a Swedish-based program with the aim to map of all the human proteins in cells, tissues and organs using integration of various omics technologies, including genomics, transcriptomics, antibody-based ...
First, single-cell features and class probability were extracted for the 12,770 human proteins mapped in the Cell Atlas of the Human Protein Atlas (HPAv20). The feature embedding was reduced by UMAP and colored by image-level labels with high prediction probability (Methods). Clusters with ...
THE HUMAN PROTEIN ATLAS - IMPLICATIONS FOR HUMAN BIOLOGY, DRUG DEVELOPMENT AND PRECISION MEDICINE The Human Protein Atlas (HPA) is a Swedish-based program with the aim to map of all the human proteins in cells, tissues and organs using integration of va... Matthias Uhlen - Cell Culture Engin...
The Human Protein Atlas (HPA) aims to map human proteins via multiple technologies including imaging, proteomics and transcriptomics. Access of the HPA data is mainly via web-based interface allowing views of individual proteins, which may not be optimal for data analysis of a gene set, or auto...
We thank all the participants of the Human Protein Atlas Image Classification competition. We also acknowledge the staff at Kaggle for providing a competition platform that enabled this study and the competition prize sponsors Leica Microsystems and NVIDIA. The staff of the HPA program provided valuabl...
2b). We found analogous marker expression of COL12A1 around the cartilage in the Human Protein Atlas (HPA) (Extended Data Fig. 4f), supporting cell2location mapping of PC-fibro (Fig. 2g). We identified bone development genes LRG4/6 (ref. 22) along with fibroblast markers in PC-fibros,...
Data from the Human Protein Atlas [24] (HPA) are not appropriate for completing ours as they derive from a biased a priori selection of proteins and antibody availability. Antibody-based assays can also be very variable in their sensitivity, thus making expression profiles of different proteins ...
The Human Protein Atlas (HPA: https://www.proteinatlas.org/) was utilized for further exploration about the protein levels of model genes47,48. Additionally, the HPA was also utilized to exhibit the cellular localization on the basis of immunofluorescence. Results Identification of metabolic ...