M'Charek, A. (2005) The Human Genome Diversity Project. An Ethnography of Scientific Practice. Cambridge: Cambridge University Press.M'charek, A. (2005) The Human Genome Diversity Project. An Ethnography of Sci
C. The trouble with the Human Genome Diversity Project. Mol. Med. Today 4, 242–243 (1998). Article CAS PubMed Google Scholar Fox, K. The illusion of inclusion—the “All of Us” research program and Indigenous peoples’ DNA. N. Engl. J. Med. 383, 411–413 (2020). Article Pub...
The Human Genome Diversity Project (HGDP) was launched in 1991 by a group of population geneticists whose aim was to map genetic diversity in hundreds of human populations by tracing the similarities and differences between them. It quickly became controversial and was accused of racism and 'bad ...
(1999). The Human Genome Diversity Project as a Complement to Human Population Genetics. Politics and the Life Sciences 18(2): 289–290.Bowman James E. The Human Genome Diversity Project as a Complement to Human Population Genetics. In The Human Genome Diversity Project. POLITICS and The LIFE...
Contribute 50,000 telomere-to-telomere (T2T) phased diploid reference genomes from > 20 countries to a Human Pangenome Project and expand the pangenome reference to cover most diversity; Define standards and methodologies for integrating multi-omics into precision medicine, and; ...
Section two considers the aims and origins of the Human Genome Diversity Project, and criticisms levelled against the venture by Indigenous peak bodies and anti-biotechnology groups, such as the Rural Advancement Foundation International. It examines the ways in which the United Nations Educational, ...
The 20th anniversary of the publication of the first draft of the human genome1,2 offers an opportunity to track how the project has empowered research into the genetic roots of human disease, changed drug discovery and helped to revise the idea of the gene itself....
In short, the final reference dataset was compiled with data from the Human Genome Diversity Project (HGDP)138 and the 1000 Genomes Project139. HGDP samples were retrieved as individual sequence alignment files in CRAM format [https://ftp.sra.ebi.ac.uk/1000g/ftp/data_collections/HGDP/data/]...
Illumina dataset, we merged South Asian79, Tibetan and Sherpa individuals in Nepal23,43,73, Himalayan individuals24with individuals in the Human Genome Diversity Project80(Supplementary Data6). We then merged Burmese and Thai individuals from the Simon Genome Diversity Project73. We included the sam...
To project every GWAS participant into the same principal component (PC) space, we used pre-computed PC loadings and reference allele frequencies. For reference, we used unrelated samples from the 1000 Genomes Project and the Human Genome Diversity Project and computed PC loadings and allele frequ...