The Human Genome Diversity Project (HGDP) is an international collaborative research initiativh that is being ihedeveloped under the supervision of the Human Genome Organization (HUGO). The overall goal of project is to derhiedreconstruct the evolutionary history of the world populations by ...
Using data from the HapMap and the human genome diversity project (HGDP-CEPH) and recently developed statistical methods, we studied individual genetic ... JR Huyghe,E Fransen,S Hannula,... - 《European Journal of Human Genetics》 被引量: 21发表: 2011年 The Human Genome Diversity Project ...
First, genome-wide principal components analysis (PCA) of our cohort and the reference population (i.e., 1000 Genome and Human Genome Diversity Project population (HGDP)) genotype was performed using ‘flashpcaR’ R package. Next, our cohort genotype was projected on the PC space of the ...
Underrepresented populations are often excluded from genomic studies owing in part to a lack of resources supporting theiranalyses. The 1000 Genomes Project (1kGP) and Human Genome Diversity Project (HGDP), which have recently been sequenced tohigh coverage, are valuable genomic resources because of ...
Genome-wide association study HAR: Human Accelerated Region HGDP: The Human Genomes Diversity Project iPSCs: Induced pluripotent stem cells Ka/Ks: Ratio of non-synonymous and synonymous changes KRAB: Kruppel-associated box KZFP: KRAB zinc finger protein ...
Mbuti samples (HGDP-CEPH, Human Genome Diversity Project-Centre d’Etude du polymorphisme Humain - https://cephb.fr/en/hgdp_panel.php) from the HOA were also extracted to compute f-statistics (see below). ChromoPainter and fineSTRUCTURE PREGO’s SNP-array dataset (post-QC) was phased ...
Assessing contamination using the frequency of private European alleles (as defined in the human genome diversity project) as an estimator and a fixed error rate from the observed neighbouring bases, we estimate the raw read contamination to be at most 0.8% (standard error (s.e.) 6 0.2%) (...
More specifically, this study relates to and shares some of the goals of the Human Genome Diversity Project (HGDP) [5], a worldwide survey of the genetic wealth of the human species undertaken shortly after the launch of the Human Genome Project. The HGDP ultimately aims to gain an understa...
This special feature describes the ethical issues in international collaborative research on the human genome, both regarding the Human Genome Project (HGP), which is concerned with genetic mapping, and the Human Genome Diversity Project (HGDP), which is an effort to document the genetic variation ...