It is based upon the concept that the amount of expressed gene product directly reflects the number of alleles that contribute to that gene product, such as enzyme activity.Robert S. SparkesGenetic and Metabolic Disease in PediatricsMckusick,VA.The human gene map.Clinical Genetics. 1985...
McKusick, V.A., 1986, The human gene map: The morbid anatomy of the human genome, Clin. Genet. 29 :545–588.McKusick VA (1986) The human gene map 15 April 1986. Clin Genet 29: 545–588McKusick VA (1986) The human gene map, 15 April 1986, the morbid anatomy of the human genome...
The human genome is by far the largest genome to be sequenced, and its size and complexity present many challenges for sequence assembly. The International Human Genome Sequencing Consortium constructed a map of the whole genome to enable the selection of clones for sequencing and for the accurate...
This report constitutes the seventh update of the human obesity gene map incorporating published results up to the end of October 2000. Evidence from the rodent and human obesity cases caused by single-gene mutations, Mendelian disorders exhibiting obesity as a clinical feature, quantitative trait ...
This paper presents the 12th update of the human obesity gene map, which incorporates published results up to the end of October 2005. Evidence from single-gene mutation obesity cases, Mendelian disorders exhibiting obesity as a clinical feature, transgenic and knockout murine models relevant to obe...
Belouchi, AbdelmajidBruat, VanessaCroteau, PascalDubois, DanielLittle, Randall DavidPaquin, BrunoRaelson, John VernerSegal, JonathanVan Eerdewegh, PaulBriand, SandieWOWO2008024114A1 Aug 24, 2006 Feb 28, 2008 Genizon Biosciences Inc Genemap of the human genes associated with schizophrenia...
K. The HLA genomic loci map: expression, interaction, diversity and disease. J. Hum. Genet. 54, 15–39 (2009). Article CAS PubMed Google Scholar Ligthart, S. et al. Genome analyses of >200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link ...
Properties of LD in the human genome Traditionally, descriptions of LD have focused on measures calculated between pairs of SNPs, averaged as a function of physical distance. Examples of such analyses for the HapMap data are presented in Supplementary Fig. 6. After adjusting for known confounders...
The human gene map for performance and health-related fitness phenotypes: the 2005 update. Talent identification in sport: practices and issues A complete DNA sequence and gene map of rice was established. Nearly 40% of the world's arable land is too acidic to grow wheat, mainly because of ...
the factor V, factor XII, protein C, protein S, prothrombin, thrombomodulin, and heparin cofactor II gene. The genotype data were used to integrate these 26 genes in the current genetic linkage map, and to identify closely linked AC-repeat polymorphisms. This information will benefit the ...