Cell MetabolismPavlova NN, Thompson CB: The emerging hallmarks of cancer metabolism. Cell Metab 2016, 23:27-47.Pavlova NN, Thompson CB. The emerging hallmarks of cancer metabo- lism. Cell Metab 2016;23:27-47.Pavlova, N. N. and Thompson, C. B. (2016). The emerging hallmarks of cancer...
The eight hallmarks currently comprise(Fig. 1, left) the acquired capabilities for sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing/accessing vasculature, activating invasion and metastasis, reprogramming cellular metabolism, and avoid...
The hallmarks of cancer metabolism: still emerging. Cell Metab. 2022;34(3):355–77. Article CAS PubMed Google Scholar Lunt S, Vander HM. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. Annu Rev Cell Dev Biol. 2011;27:441–64. Article CAS PubMed Google Scholar...
Metabolism in cancer metastasis: bioenergetics, biosynthesis, and beyond. Wiley Interdiscip. Rev. Syst. Biol. Med. 10, e1406 (2018). Google Scholar Elia, I., Doglioni, G. & Fendt, S.-M. Metabolic hallmarks of metastasis formation. Trends Cell Biol. 28, 673–687 (2018). CAS PubMed ...
2000年,Douglas Hanahan和Robert A. Weinberg在《cell》上发表文章:The Hallmarks of Cancer,这篇综述性文章介绍了肿瘤细胞的六大基本特征,被称为肿瘤学研究的经典论文,至今的引用次数已经破万,而在2011年3月新出版的Cell杂志上,Weinberg教授又发表了一篇升级版综述:Hallmarks of Cancer: The Next ...
我真正地爱您,不想要失去您。 [translate] a运动员们忙于训练 The athletes are busy with the training [translate] aThe essential hallmarks of cancer are intertwined with an altered cancer cell-intrinsic metabolism. 癌症根本标记交错与修改过的癌症细胞内在新陈代谢。 [translate] ...
47、ened malignancy Reprogramming Energy Metabolism Under aerobic conditions, normal cells process glucose,first to pyruvate via glycolysis in the cytosol and thereafter to carbon dioxide in the mitochondria; under anaerobic conditions, glycolysis is favored Cancer cells can reprogram their glucose meta 48...
(Nigro et al.2014). Microbiota regulates 10% of the host’s transcriptome, including genes related to immune response, metabolism, and cell cycle control and proliferation. And while ileal and colonic crypts are regulated differently, microbiota enriches regulatory factors that control cell ...
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell 149, 656–670 (2012). This study illustrates how oncogenic Kras signalling regulates metabolism through MAPK signalling and MYC activity in pancreatic cancer. Article CAS PubMed PubMed Central Google Scholar...
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