Compartmentalization of the gut microbiota is thought to be important to system function, but the extent of spatial organization in the gut ecosystem remains poorly understood. Here, we profile the murine colonic microbiota along longitudinal and lateral axes using laser capture microdissection. We found...
(also known as the brain-gut axis), is thought to be involved in many regular functions and systems within the healthy body, in addition to the pathogenesis of many diseases from neurological and degenerative conditions to autoimmune diseases. The gut-brain axis is now being investigated as a ...
The gut microbiome is known to be sensitive to changes in the immune system, especially during autoimmune diseases such as Multiple Sclerosis (MS). Our study examines the changes to the gut microbiome that occur during experimental autoimmune encephalomyelitis (EAE), an animal model for MS. We co...
So, while it’s unlikely that your doctor will be prescribing psychobiotics anytime soon, there is still much you can do on your own to optimize your microbiome right now. 1. Take a Psychobiotic Supplement You can take probiotic supplements that qualify as “psychobiotic,” but finding one ...
Gut microbiome alterations are closely related to human health and linked to a variety of diseases. Although great efforts have been made to understand the risk factors for multiple myeloma (MM), little is known about the role of the gut microbiome and alterations of its metabolic functions in ...
the gastrointestinal tract and the brain is evolving quickly. This relationship, dubbed the microbiota-gut-brain axis, is thought to be involved in many aspects of homeostasis in addition to the pathogenesis of several diseases, ranging from neurological and degenerative conditions to autoimmune ...
Dietary fat can also affect microbial composition; therefore, further studies will be required to investigate in what capacity each individual macromolecule impacts the bacterial communities and how they act in concert. Fats Consumption of high saturated and trans fat diets is thought to increase the ...
It is evident that the compositional and proportional differences in the gut microbiome are associated with the development of AID via an immunomodulatory effect of the gut microbiome. The gut microbiome may contribute to the development, persistence, and severity of AID via immunologic, metabolic, an...
Molecular docking is a computational technique that predicts the binding affinity of ligands to receptor proteins. Although it has potential uses in nutraceutical research, it has developed into a formidable tool for drug development. Bioactive substance
An ever-growing body of evidence has linked the gut microbiome with both the effectiveness and the toxicity of cancer therapies. Radiotherapy is an effective way to treat tumors, although large variations exist among patients in tumor radio-responsivenes