Among the risk factors contributing to obesity, human gut microbiome recently emerges with unprecedented intimacy in host metabolism and inflammation. With the advances in sequencing technology, more and more detailed understandings towards the intricate relationships linking gut microbiome and obesity have ...
Barlow GM, Yu A, Mathur R (2015) Role of the Gut Microbiome in Obesity and Diabetes Mellitus. Nutr Clin Pract 30(6): 787-797.Barlow GM, Yu A, Mathur R. Role of the gut microbiome in obesity and diabetes mellitus. Nutr Clin Pract. 2015;30(6):787-97....
(2016). The microbiome in obesity, diabetes, and NAFLD: what is your gut telling us? Curr. Hepatol. Rep. 15, 96-102. doi: 10.1007/s11901-016-0299-5Adams LA, Morrison M. The microbiome in obesity, diabetes and NAFLD: what is your gut telling us? Curr Hepatol Rep 2016;15:96-102....
The gut microbiota has been linked to cardiovascular diseases. However, the composition and functional capacity of the gut microbiome in relation to cardiovascular diseases have not been systematically examined. Here, we perform a metagenome-wide association study on stools from 218 individuals with athe...
Obesity and obesity-related metabolic disorders are characterized by specific alterations in the composition and function of the human gut microbiome. Mechanistic studies have indicated that the gastrointestinal microbiota can influence both sides of the energy balance equation; namely, as a factor ...
Gut microbiota dysbiosis has a significant role in the pathogenesis of metabolic diseases, including obesity. Nuciferine (NUC) is a main bioactive component in the lotus leaf that has been used as food in China since ancient times. Here, we examined whet
Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe. 2008;3:213–23.PubMedCentralPubMed 7. Ley RE, Backhed F, Turnbaugh P, Lozupone CA, Knight RD, Gordon JI. Obesity alters gut microbial ecology. Proc Natl Acad Sci ...
gut microbiome-derived metabolites and peripheral immunity by altering peripheral immune cell gene expression and cytokine release. Changes in peripheral immunity, possibly gut-derived metabolites directly, and vagus nerve trafficked gut-derived hormones can then alter phenotype of the blood brain barrier ...
(Fig.1). We also discuss the influence of the gut microbiota in the onset of obesity and metabolic diseases through molecular interactions with energy metabolism and inflammation pathways of the host. Finally, we assess the therapeutic potential of manipulating microbial ecology to prevent obesity-...
While maternal obesity is associated with significant alterations in the infant gut microbiome, studies correlating these changes with future obesity or immune dysfunction are frequently confounded by multiple disruptors of the microbiota such as cesarean delivery, perinatal antibiotic use, or postnatal ...