The Gene Expression Omnibus (GEO) database is an international public repository that archives and freely distributes high-throughput gene expression and other functional genomics data sets. Created in 2000 as a worldwide resource for gene expression studies, GEO has evolved with rapidly changing ...
The Gene Expression Omnibus (GEO) database is an international public repository that archives and freely distributes high-throughput gene expression and other functional genomics data sets. Created in 2000 as a worldwide resource for gene expression studies, GEO has evolved with rapidly changing tech...
The Gene Expression Omnibus (GEO): A Gene Expression and Hybridization Repository The GEO repository is a relational database, which required that some fundamental implementation decisions were made: (a) GEO does not store raw hybridization-array image data, although “reference” images of less ...
geoomnibusgeneexpressionrepositoryabundance TheGeneExpressionOmnibus(GEO):AGeneExpressionand HybridizationRepository [Chapter6] RonEdgar AlexLash Summary TheGeneExpressionOmnibus(GEO)projectwasinitiatedatNCBIin1999inresponsetothe growingdemandforapublicrepositoryfordatageneratedfromhigh-throughputmicroarray experiments.GE...
In the Gene Expression Omnibus (GEO) database (http://www.ncbi.nlm.nih.gov/geo/), we selected GSE158055 for single-cell analysis and downloaded the sequencing data of the epithelial cells. Single-cell analysis was performed using the ‘Seurat’ package in the R (4.2.1). After standardizin...
Using the Gene Expression Omnibus (GEO) database, several key differentially expressed genes (DEGs) were identified, and their biological processes and pathways found to be closely associated with endometrial cancer. In addition, we found that endometrial cancer cells-derived exosomal miRNA targets the...
Expression profiles were downloaded from the Gene Expression Omnibus (GEO), and differentially expressed genes (DEGs) were identified by R packages (Affy and limma). Gene functional enrichments of each dataset were performed on the DAVID database. Protein–protein interaction (PPI) network was const...
In this study, we analyzed two gene expression profiles (Table1) extracted from the National Center for Biotechnology Information Gene Expression Omnibus (GEO) database, which is a free global database of sequencing results. DEGs were identified by using the online tool GEO2R. Subsequently, the...
The data set is deposited in the Gene Expression Omnibus (GEO) database [GSE14303] at the following site: http://www.ncbi.nlm.nih.gov/geo/. Spot intensity reports were imported into data mining software, GeneSight 3.0 (BioDiscovery Inc., El Segundo, CA, USA). Briefly, data was pre-...
The gene expression omnibus (GEO) is the world’s largest public repository of functional genomic data. Despite its broad use in secondary genomic analyses, the temporal trends in the characteristics of genomic data on GEO, including experimental procedures, geographic origin, funder(s), and relate...