Messenger RNA (mRNA) vaccines against COVID‐19 are the first authorized biological preparations developed using this platform. During the pandemic, their administration has been proven to be a life‐saving intervention. Here, we review the main advantages of using mRNA vaccines, identify further ...
Conventional mRNA vaccines consist of messenger RNA that carries the genetic code for covid’s spike protein. Once that mRNA enters the body, it gets translated into proteins by the same cellular machinery that translates our own messenger RNA. Self-amplifying mRNA vaccines contain a gene that...
global producer of poliomyelitis and influenza vaccines EVolutive Facilities Pushing Manufacturing to the Next Level Fully digitalized, our EVolutive Facilities (EVF) will enable more responsive and flexible manufacturing across multiple vaccine and biological platforms including mRNA, while minimizing our impac...
Messenger RNA (mRNA) is an emerging class of therapeutic agent for the prevention and treatment of a wide range of diseases. The recent success of the two highly efficacious mRNA vaccines produced by Moderna and Pfizer–BioNTech to protect against COVID-19 highlights the huge potential of mRNA ...
The impressive flexibility and speed with which mRNA vaccines can be developed pave the way for using the new platform also for vaccines against other infectious diseases. In the future, the technology may also be used to deliver therapeutic proteins and treat some cancer ...
Separately, mRNA technology, by now well established thanks to its use in the world’s first COVID-19 vaccines, is poised to disrupt not only infectious diseases but also cancer and immunological disorders. And finally, ADCs are rapidly transforming oncology, with eight of 13 FDA approvals for...
The emergency use authorizations (EUAs) of two mRNA-based severe acute respiratory syndrome coronavirus (SARS-CoV)-2 vaccines approximately 11 months after publication of the viral sequence highlights the transformative potential of this nucleic acid technology. Most clinical applications of mRNA to date...
The extraordinary success of mRNA vaccines against coronavirus disease 2019 (COVID-19) has renewed interest in mRNA as a means of delivering therapeutic proteins. Early clinical trials of mRNA therapeutics include studies of paracrine vascular endothelial growth factor (VEGF) mRNA for heart failure and...
Charting the Future of Vaccines The article discusses the future of mRNA vaccines, discussing their unique attributes, benefits and limitations in comparison to traditional vaccines. Topi... G Playter - 《Pharmaceutical Technology》 被引量: 0发表: 2023年 Securing our future - The value of veterinar...
given the success rate of the Covid-19 vaccine — even though respiratory viruses are a terrible tar, they’re really hard for any vaccine technology to be very good — for other viruses, the mRNA vaccines may work much better.