WEGIEL, J.WISNIEWSKI, H.WANG, K. C.KUJAWA, M.LACH, B.Alzheimer Disease & Associated DisordersWegiel J, Wisniewski H, Wang KC, Kujawa M, Lach B: The function of astrocytes in plaques in Alzheimer disease (abstr). Alzheimer's Disease Assoc Dis 1988, 2: 265...
astrocytes are actively involved in cell signaling in normal physiological states; manipulating various aspects of astrocytic cell signaling in vivo has revealed that astrocytes are key players in controlling healthy behavior in the absence of pathophysiology. Unfortunately, the study of astrocyte function ...
astroglia,macroglia- tissue consisting of large stellate neuroglial cells fibrous astrocyte- star-shaped cells with long processes; found in the white matter of the brain and spinal cord protoplasmic astrocyte- a kind of astrocyte found in the grey matter ...
2c,e). They share key marker genes that are fundamental for the development and function of astrocytes, such as SOXE3 (Sox9), HES5 and SLC1A2 (Fig. 3a and Extended Data Fig. 9a). However, like in other anamniotes (for example, fishes and amphibians), lamprey astrocytes are mainly ...
The main elements of the central nervous system are the brain and the spinal cord. It contains millions of neurons and glial : astrocytes, oligodendrocytes, and microglia. The main role of the CNS is to process information, analyze signals, and activate effector organs. The role of the glial...
While astrocytes certainly contribute to classic inflammatory processes (e.g. cytokine release, waste clearance, and tissue repair), newly emerging technologies for measuring and targeting cell specific activities in the brain have uncovered essential roles for astrocytes in synapse function, brain ...
Immune function of astrocytes (p 180-190) The ability of astrocytes to produce a wide array of chemokines and cytokines is discussed, with an emphasis on the immunological properties of these mediators. The significance of astrocytic antigen presentation and chemokine/cytokine ... Yuanshu,Dong,Etty...
the function of the NADPH-oxidase complex and induces Ca2+release, as described above. In addition, renin and its precursor prorenin also act on the corresponding receptors (Fig.1). Binding of prorenin to its receptor provides prorenin with catalytic properties similar to those of renin. ...
Y. Astrocytes: a cellular player in Aβ clearance and degradation. Trends Mol. Med. 9, 279–280 (2003). Article CAS PubMed Google Scholar Abbott, N. J., Patabendige, A. A., Dolman, D. E., Yusof, S. R. & Begley, D. J. Structure and function of the blood–brain barrier. ...
Astrocytes releasing glucose- and/or glycogen-derived lactate and glutamine play a crucial role in shaping neuronal function and plasticity. Little is known, however, how metabolic functions of astrocytes, e.g., their ability to degrade glucosyl units, are affected by the presence of neurons. To...