C phase is defined as the temporal interval between the G1–S transition and the end of mitosis when CDK activity is present. Organomegaly The abnormal enlargement of organs. Mitotic catastrophe A death resulting from failure of a cell to arrest before mitosis following DNA damage, resulting in...
Strikingly, at the end of mitosis, Cenp-F was strongly recruited to mitochondria (Fig. 1b, bottom). The profound difference in recruitment between early and late mitosis (Fig. 1c) was not merely due to differences in Cenp-F levels (Supplementary Fig. 2C), and must therefore indicate a ...
endometriosis- the presence of endometrium elsewhere than in the lining of the uterus; causes premenstrual pain and dysmenorrhea adenomyosis pathology- any deviation from a healthy or normal condition Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc. ...
The MEN is also required for cytokinesis, but its main role is to control inactivation of mitotic cyclin-dependent kinases (CDKs) at the end of mitosis, and thereby regulate mitotic exit. Each revolves around a Ras-family GTPase and involves several protein kinases, and SIN and MEN proteins ...
The pairs of chromatids then separate, each strand of a pair moving to an opposite end of the cell. When a new membrane forms around each of the two groups of chromosomes, division of the nucleus is complete. The four main phases of mitosis are prophase, metaphase, anaphase, and ...
It has been also shown that the values of the dose of cell irradiation and of the mean duration tG2" of the subphase G2" localized at the end of phase G2 and preceded by the G2-block satisfy the next formula: Ig D = -a . Ig tG2" + b. 展开 ...
Next, paired-end sequencing was performed on the Illumina HiSeq3000 system (Illumina, San Diego, CA, USA) with a sequencing depth of 250–270 M read-pairs per sample. Quality control analysis of pre-processing data was performed using FastQC. ST raw data annotation, filtering, and processing...
Inmeiosis, diploid cells split into two cell and then again with an end result of four haploid cells. The new cells receive only one copy of each chromosome rather than two and have only half the number of chromosomes as the parent cell. ...
Thus, SBS1, ID1 and ID2 may all be generated during DNA replication at mitosis. The number of ID5 mutations correlated with the number of SBS40 mutations, and the mutational processes that underlie these two age-correlated signatures may therefore contain common components. ID8, which is ...
Mitosis relies on forces generated in the spindle, a micro-machine composed of microtubules and associated proteins. Forces are required for the congression of chromosomes to the metaphase plate and their separation in anaphase. However, besides forces, torques may exist in the spindle, yet they ...