Figure A1. The drug discovery processHerrling PL (2005) The drug discovery process. Prog Drug Res 62: 1-14.Herrling PL. The drug discovery process. In: Imaging in drug discovery and early clinical trials. Springer; 2005:1-14.δ Herrling P. L. (2005). The drug discovery process. En:...
Needed: system dynamics for the drug discovery process A system dynamics structure to characterize the link between technology and critical management decisions in the drug discovery process (DDP) is needed. Th... S Sirois,LM Cloutier - 《Drug Discovery Today》 被引量: 9发表: 2008年 The ...
"Mostnew drugstested on human subjects fail inclinical trialsbecause the therapeutic response is insufficient. Developing a strategy that infers potential clinical responses early in the drug discovery process would significantly improve drug candidate selection," said Besma Benredjem, the study's co-le...
MediChem speeds the drug discovery process - Identifies targets and chemical resources needed to develop new drugs 来自 ResearchGate 喜欢 0 阅读量: 22 作者: C Potera 摘要: Now that the human genome has been sequenced, understanding the structure and function of each gene product or protein is ...
Bioinformatics in the Drug Discovery Process Introduction 鈹 Bioinformatics is the part of molecular biology that involves working with biological data, typically using computers, with the goal of ena... S Pollock,H Safer,P Rosen 被引量: 0发表: 2004年 Utility of homology models in the drug di...
Nonclinical pharmacodynamic studies in the drug discovery process: Who, what, how, whenMATTEUORIENATE AMATTEUORIENATE BALDOSE REDUCTASEMATTEUCCIA ORIENTALIS.doi:10.1002/ddr.430320403Ronald D. SmithJohn Wiley & Sons, Ltd.Drug Development Research
The RTC “focuses on project work in the early stages of the drug discovery process, including target identification, high through-put screening, hit-to-lead chemistry, optimization, and chemical tool production.” One of the current RTC projects is the Kinases Platform, a strategy to “identify...
Suggestions for improving the drug discovery process include morein vivotesting earlier in the drug discovery process, allowing medicinal chemists to champion their drug candidate during its development; and passing on the tacit knowledge of experienced medicinal chemists to their younger colleagues. ...
Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effectivethoroughly examines the current state of pharmaceutical research and development by providing chemistry-based perspectives on biomedical research, drug hunting and innovation. The book also considers the interplay of stake...
Since drug research can be a high-risk, high-payoff industry, it is important to researchers to effectively and strategically manage the drug discovery process. This book takes a closer look at increasing pre-approval costs for new drugs and examines not only why these increases occur, but ...