WFDC1/ps20 protein has been previously established as a growth suppressor of the prostate cancer cell line PC3. It maps to chromosome 16q23.1, a region of frequent loss of heterozygosity, familial association, and genomic loss in prostate cancer. We, therefore, chose to examine WFDC1/ps20 ...
et al. Interferon regulatory factor 3 activates p53-dependent cell growth inhibition. Cancer Lett. 242, 215–221 (2006). Article CAS PubMed Google Scholar Galluzzi, L., Buque, A., Kepp, O., Zitvogel, L. & Kroemer, G. Immunogenic cell death in cancer and infectious disease. Nat. Rev...
S4b). Therefore, while La knockdown inhibited the formation of osteoclast syncytia, it did not grossly impact osteoclast differentiation or machinery critical for cell-cell fusion. To further explore the mechanism by which La influenced the formation of osteoclasts but not their differentiation, we ...
Encompassing all life science research fields, Cell & Bioscience, official journal of the Society of Chinese Bioscientists in America, is a forum for ...
2017年,Shaverdian等[54]对于晚期非小细胞肺癌(non-small cell lung cancer,NSCLC)接受人源化PD-1单克隆抗体帕博利珠单抗(pembrolizumab)免疫治疗的Ⅰ期KEYNOTE-001研究进行了二次分析,发现相较于从未接受放疗的患者,在帕博利珠单抗治疗前(中位间隔时间9个月)接受放疗的患者有显著增加的生存获益,提示放疗联合帕博利珠...
and Rho-dependent serum response factor signalling, undergo differential regulation under pathological conditions [6]. While cell-cell coupling was once perceived as a static anatomical structure, recent research underscores the impact of cardiac remodelling processes on GJs in conditions like atrial fibril...
The readers should note that in June's edition of the Journal Citation Reports (JCR) the impact factor of Microbial Cell Factories was erroneously reflected due to a failure in the system aggregating citations. The fault has been corrected in November's edition (on November 20), so the ...
The mRNA content in sperm is relatively low compared to any other cell type, and their origin (i.e. pre- versus post-meiotic) and role need further investigation. The three remaining families (i.e. miRNAs, piRNAs and tRNAs) belong to the group of ‘small non-coding’ RNAs (sRNAs) as...
(Supplementary Data6) and were reproducible across replicates, and by comparing them with a previously generated dataset from the same cell type54(Supplementary Fig.5a, b). Considering the high level of correlation, we generated unique contact matrices merging the three replicates, obtaining ~927 ...
The Plant Cell publishes novel research of special significance in plant biology, especially in the areas of cellular biology, molecular biology,