The readers should note that in June's edition of the Journal Citation Reports (JCR) the impact factor of Microbial Cell Factories was erroneously reflected due to a failure in the system aggregating citations. The fault has been corrected in November's edition (on November 20), so the ...
WFDC1/ps20 protein has been previously established as a growth suppressor of the prostate cancer cell line PC3. It maps to chromosome 16q23.1, a region of frequent loss of heterozygosity, familial association, and genomic loss in prostate cancer. We, therefore, chose to examine WFDC1/ps20 ...
We cover both the use of microbes to produce whole foods out of their biomass and as cell factories to make highly functional and nutritional ingredients. The technical, economical, and societal limitations are also discussed together with the current and future perspectives....
A crucial step in the analysis of single-cell data is annotating cells to cell types and states. While a myriad of approaches has been proposed, manual labeling of cells to create training datasets remains tedious and time-consuming. In the field of machine learning, active and self-supervised...
已有研究表明,间充质干细胞(Mesenchymal stem cell, MSC)移植是一种很有前途的治疗脊髓损伤的策略,但免疫排斥反应限制了其应用。骨髓间充质干细胞(Bone marrow mesenchymal stem cell,BMSC)的治疗效果主要取决于其可溶性旁分泌因子的释放,其中外泌体(EXO)对于旁分泌作用是必不可少的。骨髓间充质干细胞来源的外泌...
and Rho-dependent serum response factor signalling, undergo differential regulation under pathological conditions [6]. While cell-cell coupling was once perceived as a static anatomical structure, recent research underscores the impact of cardiac remodelling processes on GJs in conditions like atrial fibril...
Mol Biol Cell. 2001;12:323–37. CAS PubMed PubMed Central Google Scholar Canadell D, García-Martínez J, Alepuz P, Pérez-Ortín JE, Ariño J. Impact of high pH stress on yeast gene expression: a comprehensive analysis of mRNA turnover during stress responses. Biochimica et ...
Muscle-invasive bladder cancer (MIBC) is a highly aggressive disease with a poor prognosis. B cells are crucial factors in tumor suppression, and tertiary lymphoid structures (TLSs) facilitate immune cell recruitment to the tumor microenvironment (TME).
Current dogma is that there exists a hematopoietic pluripotent stem cell, resident in the marrow, which is quiescent, but with tremendous proliferative and differentiative potential. Furthermore, the hematopoietic system is essentially hierarchical with
Predatory bacteria feed upon other bacteria in various environments. Bdellovibrio exovorus is an obligate epibiotic predator that attaches on the prey cell surface, where it grows and proliferates. Although the mechanisms allowing feeding through the pre