Membrane Proteins in Vivo and in Silico: Getting the Best of Two Worldsmembrane proteinsproteomictopology predictionMembrane protein research has gained a lot of momentum in recent years: high-resolution structures are being produced at an increasing rate, membrane proteomics is coming on line, and ...
The field of Membrane Protein Structural Biology has grown significantly since its first landmark in 1985 with the first three-dimensional atomic resolution structure of a membrane protein. Nearly twenty-six years later, the crystal structure of the beta2 adrenergic receptor in complex with G protein...
A form of cellular catabolism that is responsible for the removal of large cellular components (for instance, protein aggregates or damaged organelles). Autophagy involves the inclusion of these components within double-membraned vesicles (termed ‘autophagosomes’), which then undergo fusion with lyso...
The Membrane Protein Data Bank (MPDB) is an online, searchable, relational database of structural and functional information on integral, anchored and peri
MAVS has a C-terminal transmembrane (TM) domain that anchors to the mitochondrial outer membrane; a middle proline-rich region (PRR) that binds to the tumor necrosis factor receptor-related factor (TRAF) family members; and an N-terminal caspase-recruitment domain (CARD) that interacts with th...
The lysis buffer used for a particular application depends on the target proteins that will be immunoprecipitated, because the location of the protein in the cell (e.g., membrane, cytosol, nucleus) affects the ease of release during ...
New technology platforms to identify new protein-protein interactions at the cell membrane Dualsystems the experts for protein-protein interactions at the cell membrane Dualsystems Biotech AGis specialises in elucidating protein-protein interactions in the living cells especially at the cell membrane. Dualsys...
In-vivo identification of direct electron transfer from Shewanella oneidensis MR-1 to electrodes via outer-membrane OmcA–MtrCAB protein complexes. Electrochim. Acta 56, 5526–5531 (2011). CAS Google Scholar Okamoto, A., Nakamura, R., Ishii, K. & Hashimoto, K. In vivo electrochemistry of ...
Protein-protein interaction on the cell membrane of the living cell You are here:Home New technology platforms to identify new protein-protein interactions at the cell membrane Dualsystems Biotech AGis specialises in elucidating protein-protein interactions in the living cells especially at the cell memb...
LDL receptor related protein (LRP)5 or LRP6 (Fig.7a). Furthermore, we observed that Amuc_1409*and E-cadherin were co-localized in the plasma membrane of intact cells, providing additional evidence for their interaction (Supplementary Fig.5a). We used His-tagged P9 (secreted protein) and His...