GE and PFMGs’ aims are to integrate genomics into routine healthcare in order to improve diagnosis for rare disease and cancer and better target personalised treatment options. In the UK, GE launched the 100,000 Genomes Project (100 kGP) in 2012 with the aim of sequencing 100 k genomes fr...
Aim: In the postgenomic era, in many European countries, very little is known regarding the level of awareness of healthcare professionals with respect to pharmacogenomics and personalized medicine. Methods: Here, we report the findings of an in-depth study, involving 86 pharmacists and 208 ...
environmental factors or preexisting medical condition (Evangelou, 2018).Unlike case report studies, GWAS usually aim to identify different genetic variants with different effect sizes and are not limited to a single gene as in the case of case-report studies of monogenic inborn errors of immunity...
17-24 The aim of this study is to assess clinical and biological characteristics as well as the prognosis of patients with LE with genetically determined deficiency of C2. To avoid specialty-related disease subsets, we designed this as a laboratory-based study including 72 subjects with a C2 ...
immunotherapy is widely employed, but reliable predictive markers are not available yet. Liquid biopsy has the potential to face the two issues and to increase its role in advanced NSCLC in the next future. The aim of this review is to summarise the main clinical applications of liquid biopsy ...
The aim of this paper is to explore how patients and other members of the public engage with the process of orphan drug development. Methods Patient advisory group A Patient Advisory Group (PAG) were convened prior to the funding application, and met regularly to discuss the scope and content...
The main aim of the MUREEP is to build multi-level research ethics capacity in Uganda, specifically by: 1) developing and implementing a curriculum for research ethics education and training, leading to (a) a Master of Public Health degree with a focus on research ethics and (b) a ...
The aim of this study is to evaluate the impact of a new diatomaceous earth/peat AD cell carrier on the genetic diversity, survival and morphological characteristics of bacterial communities, as well as the intensity of biofilm formation—in the anaerobic digestion process. The state-of-the-art ...
The aim of the IDrug study was to compare effects of an individualized risk assessment for ADRs with a standardized risk assessment to improve safety of drug treatment in patients that are at high risk for bleeding and thromboembolic ADRs, thereby focusing on older, multi-morbid and multi-medicat...
aim for others’ proven end states; this gives us a better bearing on our progress. Being at the frontier exploring the next generation is most resource-intensive. The followers don’t bear exploration costs — they’re always just following. If Google/Anthropic succeed in their exploration area...