genomicsrisk factorsstatisticsEarlier identification of high coronary artery disease (CAD) risk individuals may enable more effective prevention strategies. However, existing 10-year risk frameworks are ineffective at earlier identification. We sought to understand how the variable importance of genomic and ...
- 《Genetics in Medicine Official Journal of the American College of Medical Genetics》 被引量: 61发表: 2010年 Confronting real time ethical, legal, and social issues in the Electronic Medical Records and Genomics (eMERGE) Consortium. Purpose: Paraoxonase 1 (PON1) polymorphisms have been ...
Personalized medicineUrological cancersGenomicsProteomicsA better understanding of key regulatory pathways involved in cancers has led to the development of molecularly targeted therapies. Molecular profiling based on genomics, proteomics, and metabolomics in tumors provides clinicians with the necessary ...
Hum Genomics 12(19):1–15 Google Scholar Mittelstadt BD, Floridi L (2016) The ethics of big data: current and foreseeable issues in biomedical contexts. Sci Eng Ethics 22(2):303–341 Article PubMed Google Scholar Check Hayden E (2013) Privacy protections: the genome hacker. Nature 497...
in the shadow of public awareness, total attributable annual deaths are similar to, or exceeds, global mortalities due to malaria, tuberculosis or HIV. The impact of fungal infections has been exacerbated by the steady rise of antifungal drug resistant strains and species which reflects the ...
Genetic studies have typically inferred the effects of human impact by documenting patterns of genetic differentiation and levels of genetic diversity among potentially isolated populations using selective neutral markers such as mitochondrial control re
Genetic studies have typically inferred the effects of human impact by documenting patterns of genetic differentiation and levels of genetic diversity among potentially isolated populations using selective neutral markers such as mitochondrial control re
Ectopic expression of Oct4, Sox2, Klf4 and c-Myc can reprogram somatic cells into induced pluripotent stem cells (iPSCs). Attempts to identify genes or chemicals that can functionally replace each of these four reprogramming factors have revealed that ex
evolutionary tree of marine organisms. Genomics is a highly dynamic research field. Hence, rapid developments in genomics can afford new opportunities for applications in marine environment, particularly in the areas of Fish genome resources conservation and genetic enhancement....
Moreover, this corroborates the predictive utility of serum markers in HCC patients. The integration of SIPS offers a pragmatic and easily calculable tool for prognosticating the outcomes of HCC patients, thereby facilitating the development of robust prognostic models. Recent advances in genomics, ...