TGFbeta2 exposure of APCs induces TNFalpha production and shifts the ratio of TNFR1:TNFR2, favoring the latter. Autocrine TNFalpha signaling through TNFR2 inhibits IL-12 production and enables the APCs to induce ACAID when injected into naive mice.S. Masli...
flr-2 gene, which controls the growth rate of flr-1, flr-3 and flr-4 mutants, encodes a putative TGF-b antagonist.Oishi, ATakeuchi, MIshihara, TKatsura, I