结论:TGFB1和TGFBR2基因多态改变可能与中国华东宜兴地区汉族人群胃癌遗传易感性相关。周炎靳光付蒋国军王洪敏谈永飞丁伟良王莉娜陈文森柯巧沈靖癌症:英文版周炎;靳光付;蒋国军;王洪敏;谈永飞;丁伟良;王莉娜;陈文森;柯巧;沈靖;徐耀初;沈洪兵.TGFB1和TGFBR2基因多态与胃癌遗传易感性的关系.癌症:英文版.2007.581-585周炎,...
目的研究TGFB1 C-509T、T+29C和TGFBR2 G-875A与中国女性乳腺癌遗传易感的相关性,并阐述这三个多态位点与不同雌激素受体(ER)、孕激素受体(PR)和人类表皮生长因子受体-2 (HER2)表达水平乳腺癌易感性的关系。 方法从170例乳腺癌组织(包括82例新鲜乳腺癌组织、88例石蜡包埋乳腺癌组织)和178例无肿瘤病史女性的...
目的:对14例马凡综合征(Marfan syndrome, MFS)患者的原纤蛋白-1(fibrillin-1, FBN1)基因和转化生长因子-?受体2(Transforming Growth Factor Beta Receptor TypeⅡ,TGFBR2)基因进行基因突变筛查,以明确这些MFS患者FBN1基因和TGFBR2基因突变的情况,并观察基因突变与...
tgfbr2抑制剂 (共 2
Several polymorphisms have been identified in TGFB1 and TGFBR2 genes, including those associated with the regulation of TGF-β1 levels and TGF binding to its receptor. The decrease of TGF-β1 levels and the disruption of TGF TGF-β1 signaling can cause abnormal placentation, hypoxia, and ...
TGFB1 and TGFBR2 functional polymorphisms and risk of esophageal squamous cell carcinoma: a case- control analysis in a Chinese population. J Cancer Res Clin Oncol. 2008 ;134:345-351.Jin, G., Deng, Y., Miao, R. et al. (2008). TGFB1 and TGFBR2 functional polymorphisms and risk of ...
Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population. Int J Cancer 120: 1330 -1335, 2007.Jin,G,Wang,L,Chen,W,Hu,Z,Zhou,Y,Tan,J,Hua,Ding,Shen,Zhang,X,Xu,H.Variant alleles of TGFB1 and TGFBR2 are associated with a ...
89 Influence of functional genetic variants of TGFβ1/TGFβR2 pathway in prostate cancer developmentingentaconnectEUROPEAN JOURNAL OF CANCER -SUPPLEMENT-TeixeiraA.L.RibeiroR.GomesM.PereiraC.LoboF.FragaA.Calais-da-SilvaPinaMedeiros
Transforming growth factor |[beta]|1 (TGF|[beta]|1; TGFB1); TGF|[beta]| receptor II (TGF|[beta]|-R2; TGFBR2)Patient sample and rodent studies suggest inhibiting TGFβ1 signaling in bone could help treat OA. Further details on the research, next steps and licensing status are discussed...
Transforming growth factor-β1 (TGFB1); transforming growth factor-β receptor 1 (TGFBR1; ALK5); TGFBR2 (TGFβ-RII)doi:10.1038/scibx.2013.895Studies in human samples suggest inhibiting TGFBR1 or TGFBR2 could help treat allergy-related conditions.Springer...