Kaynar K, Ulusoy S, Ovali E, Vanizor B, Dikmen T, Gul S (2005) TGF-β and TNF-α producing effects of losartan and amlodipine on human mononuclear cell culture. Nephrology 10:478–482 View ArticleKaynar K, Ulusoy S, Ovali E, et al: TGF-beta and TNF-alpha producing effects of ...
TGF beta-1 and TNF alpha expression in the epidermis of patients with epidermodysplasia verruciformis. J Invest Dermatol. 1991; 97 :862–867.Majewski S, Hunzelmann N, Nischt R, et al. TGFβ-1 and TNFα expression in the epidermis of patients with epidermodysplasia verruciformis. J ...
1)TGF-β激活细胞凋亡或激活细胞增殖这种双重作用的实现可能需要一种TGF-β浓度的阈值样开关,在毛囊生长周期的不同阶段与骨形态发生蛋白 (BMP) 和肿瘤坏死因子 (TNF) 协同作用; 2)模型与生长期启动的高激活剂-低抑制剂理论一致; 3) 推测 TNF 可能比 TGF-β 更有效地启动衰退期,可能分两步合作; 4)基因敲除...
1)TGF-β激活细胞凋亡或激活细胞增殖这种双重作用的实现可能需要一种TGF-β浓度的阈值样开关,在毛囊生长周期的不同阶段与骨形态发生蛋白 (BMP) 和肿瘤坏死因子 (TNF) 协同作用; 2)模型与生长期启动的高激活剂-低抑制剂理论一致; 3)...
Levels of tumour necrosis factor (TNF)-±, transforming growth factor (TGF)-, and interleukin (IL)-10 in plasma of pulmonary tuberculosis (TB) patients and... J. O.Olobo,M.Geletu,A.Demissie,... - 《Scandinavian Journal of Immunology》 被引量: 134发表: 2010年 Circulating TNF-α, TGF...
另外，TGFβ 信号传导除了经典与非经典传导途径以外还受其他途径的影响，如WNT、Hippo、Notch、IFN、TNF 和 RAS 途径。如 Varelas X 等人研究发现，Hippo 通路能够感知细胞密度，并通过调节转录调节因子 YAP/TAZ 的亚细胞定位来控制组织生长。高密度细胞能促进与 TAZ/YAP 相互作用的 Crumbs 复合物的组装，促进 TAZ/...
Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF- kappaB-mediated ... ML Cho,SY Min,SH Chang,... - 《Immunology Letters》 被引量: 74发表: 2006年 Transforming growth factor beta 1(TGF-b1) down-regulate...
Transforming growth factor-beta stimulates the production of the extracellular matrix, whereas TNF-alpha has antifibrotic activity. Understanding the molecular mechanism underlying the antagonistic activities of TNF-alpha against TGF-beta is critical in the context of tissue repair and maintenance of tissue...
Recently we reported that TNFalpha activates the extracellular regulated kinase pathway in fibroblasts leading to a 200-400% increase in TGFbeta(1) mRNA and protein. The mechanism of TNFalpha induction of TGFbeta(1) expression appears to be complex, involving both transcriptional and post-...