In control day 1 or day 3 cultures, TNF-alpha and/or TGF-beta1 had little or no effect on the synthesis of type II cellular proteins, independent of whether the cells were exposed to dust. With PSOC 867 exposure, where ECM protein synthesis is elevated, TNF-alpha and TGF-beta1 further...
摘要: Tuberculosis (TB) is the main cause of death by infection diseases worldwide. Considering that NO, TNF-alpha and TGF-beta participate a great deal in TB immunopathogenesis, we wished to a DOI: doi:10.1016/j.imlet.2004.09.008 被引量: 16 年份: 2005 收藏...
The Journal of experimental medicine 1999 - Figure 3 CT treatment selectively suppressed IL-12 p70 and TNF-alpha, but not IL-10, TGF-beta 1 , or IL-6. Human monocytes (2 x 10 6 cell/mL) were stimulated with SAC (0.01%) and IFN-gamma (100 ng/mL) in the presence or absence of ...
R&D 240-B-002 R&D Recombinant Human TGF-beta 1. kit 3150 R&D 236-EG-200 R&D Recombinant Human EGF, CF kit 1580 R&D 233-FB-025 R&D Recombinant Human FGF basic(146 aa):25ug 25ug 2270 R&D MAB2020 R&D Human/Rat OV-6 MAb (Clone OV-6) kit 3720 R&D 215-GM-010 R&D Recombinant Human ...
Transforming growth factor-beta stimulates the production of the extracellular matrix, whereas TNF-alpha has antifibrotic activity. Understanding the molecular mechanism underlying the antagonistic activities of TNF-alpha against TGF-beta is critical in the context of tissue repair and maintenance of tissue...
Increased production of type I collagen is a common hallmark of fibrotic diseases in various organs including the liver. This increase is exerted mainly at the level of transcription, and transforming growth factor-beta (TGF beta) is the key factor in stimulating gene transcription. We have previo...
An integrated expression profiling reveals target genes of TGF-beta and TNF-alpha possibly mediated by microRNAs in lung cancer cells PloS One, 8 (2013), p. e56587 CrossrefView in ScopusGoogle Scholar 37. H.L. Wright, H.B. Thomas, R.J. Moots, S.W. Edwards RNA-seq reveals activation...
作为胞外信号分子,TGF-beta1蛋白在多种细胞中进行表达,并作为胞外信号分子参与免疫功能,细胞增殖和细胞分化等生物学过程。该产品推出后,公司陆续从生物材料中纯化了几种细胞因子产品并推向市场。天然蛋白类产品的成功推广,加速了R&D Systems在细胞因子市场的开拓。公司于1985年形成Growth Factor事业部(现Biotechnology事业...
The amount of production was 19.8 ng/ml of IL-6 by PBMC, 4.1 ng/mL of TNF by PBMC and 34.4 pg/mL of TGF-by PBMC. The immunoreactivity to IL-6, TNF-and TGF-were detected on monocytes in LPS-stimulated PBMC. Some of lymphocytes showed positive immunoreactivity to TGF-. Double ...
The aim of this study was to define the regulatory role of IL-2 and TGF-β1 on the CD103 expression and the optimal in vitro conditions for the induction/expansion of human CD4+ and CD8+ Tregs. Cord blood mononuclear...会议名称: 39th Annual Meeting of the ...