TGF-beta/ Smad2/3 signal pathway involves in U251 cell proliferation and apoptosis. Gene. 2015;562(1):76-82.Zhao HW, Li YW, Feng R, Yu JB, Li J, Zhang Y, Li JC and Wang YX: TGF-β/Smad2/3 signal pathway involves in U251 cell proliferation and apoptosis. Gene 562: 76-82, ...
6.Hepatitis B virus X protein modulates apoptosis in human renal proximal tubular epithelial cells by activating the JAK2/STAT3 signaling pathway and spring 机译:乙型肝炎病毒X蛋白通过激活JAK2 / STAT3信号通路调节人肾近端肾小管上皮细胞的凋亡 PING HE ,DAN ZHANG ,HONG LI -1 7.Shenning II Dec...
elegans, sma-2, sma-3, and sma-4, that participate in TGFbeta signaling (the Sma/Mab pathway). These three genes, along with the Drosophila Mad gene, comprise the founders of the Smad family. Smads are the primary TGFbeta signal transducer, and have had a major impact on our ...
The present invention provides a screening model of TGF-β signaling pathway drug, the reporter plasmid containing human hepatoma cell lines. 本发明的与TGF-β信号通路相关药物的药物筛选模型可靠稳定,而且操作简便,大大提高了筛选效率,降低了筛选成本,缩短了筛选周期,减少受试化合物用量,减少放射性污染. ...
Ionizing radiation induces a motile phenotype in human carcinoma cells in vitro through hyperactivation of the TGF- beta signaling pathway. Cell Mol Life Sci. 73, 427-443 (2016).Carl, C.; Flindt, A.; Hartmann, J.; Dahlke, M.; Rades, D.; Dunst, J.; Lehnert, H.; Gieseler, F.; ...
Conclusion ETV4 emerges as a driven oncogene in LC, and the ETV4/B3GNT3-TGF-beta pathway promotes proliferation, migration, invasion, and epithelial-mesenchymal transition progress of LC. Inhibition of the pathway may provide an underlying method for the prevention and treatment of LC metastasis....
This rapid progress has been the result of a synergy between classical genetic approaches and biochemical approaches, and this combined approach is likely to propel future understanding of the signaling pathway used by TGF beta.doi:10.1016/S1359-6101(96)00050-0Padgett RW...
Identification of the TAK1, as a mediator in the signaling pathway of TGF-beta; Identification of two human proteins called TAB1 and TAB2 (for TAK1 binding protein); Effect of the overproduction of TAB1 on the activity of plasminogen activator inhibitor 1 gene promoter.Shibuya...
Reports on the identification of the mouse protein kinase (TAK1) using a genetic selection based on a mitogen-activated protein kinase (MAPK) pathway in yeast. Screening of complementary DNA library to obtain a full-length clone; Analysis of the pattern of the TAK1 gene; Function of TAK1 ...
High FSH level increase endometrial atrophy through cross-talk with TGF beta signal transduction pathway in post-menopause womenEndometriosisEndometriumForkhead transcription factor-Foxp3T regulatory cellsContents Doppler ultrasonography is an important tool in the andrological evaluation in humans; however, ...