在接下来的众多分析项目中,我们仅选择Gene Regulatory Networks(GRN)中的TF-gene Interactions。 接着,选择TF-gene Interaction database,我们这里选择JASPAR数据库用于转录因子的预测。 很快,TF-gene的互作网络就完成了构建,如下,点击SIF,可下载sif格式的网络图文件导入到Cytoscape中进行分析和展示。 继续点击Proceed按钮...
involved in these motifs: miRNA–gene (miRNA represses gene expression); miRNA–TF (miRNA represses TF gene expression); TF–miRNA (TF regulates miRNA expression); TF–gene (TF regulates gene expression); gene–gene (gene and gene interaction); and miRNA–miRNA (miRNA and miRNA interaction)....
Pathfinder: mining signal transduction pathway segments from protein-protein interaction networks. BMC Bioinformatics. 2007; 8:335. doi:10.1186/1471-2105-8-335. Article PubMed PubMed Central Google Scholar Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by ...
These TFs demonstrated intricate regulatory roles either as a family or as individual members and our analysis created plausible hypotheses for combinatorial interaction among TFBSs.doi:10.1007/11427469_114Xiaobo ZhouKuang-Yu LiuGuangqin LiStephen T. C. Wong...
Background Ischemic stroke is the end phenotype of a complex interaction between various genetic and environmental factors. Objective We aimed to explore a... Bin Wang and Hongye Zhao and Li Zhou and Xiaoxia Dai and Dayu...
a, NuTi Capture-C and Micro Capture-C from the rs17713054 enhancer in Endothelial cells (HUVEC) shows specific interaction with only the promoter of LZTFL1 and an upstream CTCF site. CTCF track shows binding of the CCCTC-binding factor which acts as a boundary. b, ENCODE ChIP-seq for the...
1998: Preferential interaction of the mRNA proofreading factor TFIIS zinc ribbon with rU.dA base pairs correlates with its function Biochemistry 37(35): 12104-12112 Olmsted, V.K.; Awrey, D.E.; Koth, C.; Shan, X.; Morin, P.E.; Kazanis, S.; Edwards, A.M.; Arrowsmith, C.H. ...
接着,选择TF-gene Interaction database,我们这里选择JASPAR数据库用于转录因子的预测。 很快,TF-gene的互作网络就完成了构建,如下,点击SIF,可下载sif格式的网络图文件导入到Cytoscape中进行分析和展示。 继续点击Proceed按钮,我们可以预览构建的TF-gene互作网络,默认的效果如下。
The results demonstrate that interaction of TF with HUVEC via a binding site, independent from FVIIa, may result in regulation of a variety of genes involved in arteriosclerosis, cancer, and cardiovascular diseases.doi:10.1016/j.thromres.2010.11.024Marianne Grosser...
Our protein鈥損rotein interaction studies indicate that the flowering activation complexes in Passiflora might deviate from the hexameric complex found in the model system rice. Our results provide insights into the potential functions of FT/TFL1 gene family members during floral initiation and their ...