show that testosterone rather than synthetic "pure" androgens should be prescribed. Testosterone is converted to the superactive androgen dihydrotestosterone and to estradiol, and thus has actions via androgen receptors and both estrogen receptors (ERα, ERβ). Although muscle strength is androgen ...
Groups of genes encoding milk proteins were activated, perhaps due to testosterone being aromatized to estrogen, which in turn upregulated pituitary prolactin secretion (discussed further in this chapter). Class I major histocompatibility complex (MHC) genes were activated that may contribute to the ...
which are the pathways through which testosterone is converted to estrogen and dihydrotestosterone respectively. Excess build up of estrogen can be responsible for gynocomastia (development of female breast tissue in males) as well as bloating and water retention. Dihydrotestosterone can cause both acne...
With age, testosterone is increasingly converted to the hormone estrogen as a result of the aromatase reaction (aromatization). Higher levels of estrogen in men can lead to increased body fat and contribute to gynecomastia (enlarged breasts/man boobs), prostate cancer, heart disease, diabetes and ...
6) Testosterone gets converted into estrogen via the aromatase enzyme and normal levels of estrogen may have a beneficial impact on the arterial wall in men. Prostate cancer and testosterone: Concern about the risk of prostate cancer is still the primary reason many practitioners get nervous about...
It has long been known that aging men are at risk for having excess activity of an enzyme calledaromatase. The effect of surplusaromataseis that too muchtestosteroneis converted toestrogen.37,38 Aging men have a propensity to develop dangerouslyhigh levelsofestrogencombined with woefullyinadequatetesto...
However, excess testosterone can be converted to estrogen in the body. As such, it is unknown if testosterone therapy may increase—by contributing to more estrogen in the body—or decrease breast cancer risk in trans masculine individuals. ...
Testosterone is converted to estradiol by the activity of the aromatase enzyme, thus potentially increasing the risk of breast cancer recurrence. The use of AIs, however, may prevent such conversion and provide safety for this strategy. Prompted by this unmet need, we conducted a pilot study ...
extent in some other tissues), which is the most important source ofestrogenin men. Furthermore, testosterone is interconvertible with androstenedione, which can be converted into estrogens. When androstenedione is formed in adipose tissue, it may be converted to a form of estrogen called estrone....
A certain amount of testosterone may be necessary for healthy arteries because it's converted intoestrogen, which protects arteries from damage. As yet, no studies show that testosterone replacement protects theheartor preventsheart attacks.