TEM-1 beta-lactamase is the most widespread enzyme to confer beta-lactam antibiotic resistance to gram-negative bacteria. It is a monomeric protein that requires no metals or cofactors for activity. TEM-1 beta-lactamase efficiently hydrolyzes most penicillin and cephalosporin substrates, including nit...
TEM-1. Also responsible for the ampicillin and penicillin resistance that is seen in H.influenzae and N.gonorrhoeae in increasing numbers. Based upon different combinations of changes, currently 140 TEM-type enzymes have been described. Recombinant beta-lactamase TEM-1 contains 264 amino acids ...
P7082-10mg Recombinant β-lactamase TEM-1 10mg P7082-100mg Recombinant β-lactamase TEM-1 100mg - 说明书 1份 保存条件: -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20...
VIP 数据库导航 UNII号FX5GPC74BK 化学名TEM-1 BETA LACTAMASE (ESCHERICHIA COLI) 结构式图片 扩展信息
Hyperproduction of TEM-1 beta-lactamase in clinical isolates of Escherichia coli serotype O15. FEMS Microbiol Lett. 1990 Feb; 55 (3):319–323.Shannon, K., Williams, H., King, A. & Phillips, I. (1990). Hyperproduction of TEM-1 beta- lactamase in clinical isolates of Escherichia coli ...
Beta Lactamase TEM 1 is an enzyme encoded by the bla gene in E. coli, with its expression being constitutive. The resistance to β-lactam antibiotics is directly proportional to the number of copies of the bla gene and the enzyme synthesized. ...
CRYSTAL-STRUCTURE OF ESCHERICHIA-COLI TEM1 BETA-LACTAMASE AT 1.8-ANGSTROM RESOLUTION The X-ray structure of Escherichia coli TEM1 beta-lactamase has been refined to a crystallographic R-factor of 16.4% for 22,510 reflections between 5.0 and... C Jelsch,L Mourey,JM Masson,... 被引量: 202...
MaveyraudGroupeLaurentINSERMSamamaGroupeJean-PierreLab.European Journal of BiochemistryLenfant F, Petit A, Labia R, Maveyraud L, Samama JP, Masson JM. 1993. Site-directed mutagenesis of beta- lactamase TEM-1. Investigating the potential role of specific residues on the activity of Pseudomonas-...
TEM-109 contained both the substitutions Glu104Lys and Arg164His of the expanded-spectrum beta-lactamase (ESBL) TEM-6 and Met69Leu of the inhibitor-resistant TEM-33 (IRT-5). TEM-109 exhibited hydrolytic activity against ceftazidime similar to that of TEM-6 (k(cat), 56 s(-1) and 105 ...
Molecular analysis of beta-lactamase structure and function 2002, International Journal of Medical Microbiology Show abstract Structural and mechanistic basis for extended-spectrum drug-resistance mutations in altering the specificity of TEM, CTX-M, and KPC β-lactamases 2018, Frontiers in Molecular Biosci...