What does a telomere have to do with aging? As cells age, telomeres become shorter. Once telomeres shorten to a critical level, the cell is removed from the cell cycle and is signaled to undergo apoptosis or programmed cell death. Cells can generally divide about 20 times. However, the len...
It does , in short , precisely what a city bus is supposed to do —make it feasible for people to get around without a car . 5)动物在自己的后代一旦能够生活自理时,便不再给予关怀,但是人类,由于幼年时期太长,很难做到这一点。(indifferent to) Animals are indifferent to their young as soon ...
Mother Nature “knows” what it does. All long-lived animals well tested (not kits) have less mitROSp and less DBI (no exception). And this is the most important thing if we want to go beyound the 1.4 fold life extension effect of DRs and single gene mutant mice. Aevitas So tackling ...
S. Break-induced replication: what is it and what is it for? Cell Cycle 7, 859–864 (2008). Article CAS PubMed Google Scholar Anand, R. P., Lovett, S. T. & Haber, J. E. Break-induced DNA replication. Cold Spring Harb. Perspect. Biol. 5, a010397 (2013). Article PubMed ...
In light of this finding, it is conceivable that mammalian telomeres may also be reconstructed. However, it is unknown where the non-telomeric sequences originate from, how they are maintained and what unique characteristics the ALT cells have. Fortunately, ALT mESCs were stored chronologically ...
aMy classroom and I have the classroom aften school. 我教室和我有教室aften学校。[translate] aSjust mop it Sjust擦它[translate] aas analyzed in Refs. 2 and 3 如被分析在Refs。 2和3[translate] aThe transfer test consists of five open-ended questions examining to what extent learners apply...
Finally, although POT1 does not show a preference for its site next to the ds-ss junction in vitro (19), it could be argued that bound to shelterin, POT1 might have the ability to recognize the junction and prevent 9-1-1 loading. This hypothetical attribute is also rendered unlikely to...
and genetically meaningless sequence of DNA, what we were calling “junk DNA.” But it does have an important purpose. It's sort of like the plastic tip on each end of a shoelace. It may not help you tie your shoe, but that little plastic tip keeps the rest of the shoelace…the ...
That telomeric DNA does not always prevent rejoining raises interesting questions as to what constitutes capping, and how rapidly it occurs after DNA damage in relation to break rejoining. The prevention of degradation and control of rejoining may be mediated by telomere-specific proteins, ...
aI’m 17 years old and I am gong to university this autumn.But my mother continues to treat me as a seven-year-old.What should I do? 我是17年,并且我是锣对大学这秋天。但我的母亲继续对待我作为七年老。我该怎么办?[translate] aIn practicing one embodiment of this invention,it is generall...