Congress, TDP name candidates for TelanganaYogendra Kalavalapalli
A size of 10 nucleotides also ensures that most of the fragments are single-stranded, which is a requirement for TDP-43 binding23,24. For each list of fragments, we computed the RNA Fitness and Protein Fitness scores using catRAPID (Online Methods). The RNA Fitness score was defined as ...
A bulk infection of cells with a gRNA library targeting over 1,000 annotated proteins (>12,000 sgRNAs) was performed, followed by single cell plating on 12 microRaft arrays to screen genetic knockout clones for mislocalization of CHMP7. Positive candidates, where GFP is in the nucleus and ...
A ranked list of the transcripts (using P-values of log fold change and log differential expression from DESeq2) was submitted along with the predicted miRNA-mRNA interactions from ProMISe as custom annotations to Fatiscan (part of the Babelomics v4 suite; Medina et al., 2010). This method...