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CELL differentiationEarly during preimplantation development and in heterogeneous mouse embryonic stem cells (mESC) culture, pluripotent cells are specified towards either the primed epiblast or the primitive endoderm (PE) lineage. Canonical Wnt signaling is crucial for safeguarding naive pluripotency and ...
o, Sag current in mHb neurons wild-type (13 cells, 4 rats) and mutant (17 cells, 5 rats) Tcf7l2 rats (P = 0.1386, unpaired two-tailed t-test). p, Total distance travelled by drug-naive wild-type (n = 6) and mutant (n = 5) Tcf7l2 rats during a 60 min session. q, ...
CD8+ T cells central memory stemness T cell factor 1 (Tcf1) (Tcf7) effector differentiation Granzyme LCMV infection vaccination Introduction Infection activates very rare antigen-specific naive CD8+ T cells (Tn), which expand and differentiate into cytotoxic effector cells (Teff) that clear pathoge...
The leucine-rich repeat-containing G-protein-coupled receptor 6 (LGR6) is considered to be a stem cell marker in many normal tissues and promotes tissue development, regeneration, and repair. LGR6 is also related to the initiation and progression of some