osteocalcin signaling. T cell factor 7 (TCF7) belongs to the TCF/LEF1 family of DNA binding factors crucial for the canonical WNT/β-catenin pathway; however, TCF7 modulates Gprc6a and Ucp1 promoter activation in...
Uniprot No.: P36402 别名: (TCF-7)(T-cell-specific transcription factor 1)(T-cell factor 1)(TCF-1) 种属: Homo sapiens (Human) 蛋白长度: Full Length 来源: E.coli 分子量: 49.1 kDa 表达区域: 1-384aa 哺乳动物细胞系统: 常见的表达宿主包括CHO细胞(Chinese Hamster Ovary cells)、HEK293细胞(...
TCF7基因特异性敲除的一种T细胞。Tcf7叫做Transcription factor 7，也叫T-Cell-Factor-7，似乎与T细胞激活有关。-/-代表纯合子，说明这个基因是完全缺失的。-/+代表部分缺失，有部分细胞还是会表达。P14是改造的可以特异性识别gp33的一种T细胞，gp33-specific TCR transgenic T cells。GP33：糖蛋白表...
TCF7(transcription factor 7 (T-cell specific, HMG-box)) 基因基本信息 基因基本信息 基因简称(symbol) TCF7[HGNC][GeneCards][NCBI] 基因种类(locus group) protein-coding gene 同源简称(alias symbol) TCF-1 基因家族代码(gene_family_id) [HGNC][GenScript] ...
别名: (TCF-7)(T-cell-specific transcription factor 1)(T-cell factor 1)(TCF-1) 种属: Homo sapiens (Human) 蛋白长度: Full Length 来源: E.coli 分子量: 49.1 kDa 表达区域: 1-384aa 哺乳动物细胞系统: 常见的表达宿主包括CHO细胞(Chinese Hamster Ovary cells)、HEK293细胞(Human Embryonic Kidney ...
TCF7 基因简介 中英文全称:转录因子7(T 细胞特异, HMG框) transcription factor 7 (T-cell specific, HMG-box) 分布:核 活性:DNA结合|RNA 聚合酶II 转录因子 参与:转录|调控转录, DNA依赖|调控 转录自RNA 聚合酶II 启动子|免疫应答|Wnt 受体信号转 导途径...
鉴定TCF7-SPI1阳性和NRAS突变的T-ALL病例 外周血细胞是来自一个新诊断为未成熟的CD4/CD8双阴性T-ALL的6岁男孩,进行了全基因组和RNA测序,发现了5号和11号染色体之间的易位和NRAS的共存突变。NOTCH1、Krüppel-like factor 9、Cyclin-...
提供的TCF7 多克隆抗体为兔来源的多抗。TCF7 又称FLJ36364|MGC47735|TCF-1,其基因全名为transcription factor 7 (T-cell specific, HMG-box),蛋白号为P36402。 应用类型 WB-Ce,IHC-P 免疫原 A synthetic peptide corresponding to human TCF7。
Cell experiments showed that overexpression of TCF7 and LEF-1 enhanced proliferation and effector activation of CD4(+) T cells, reduced apoptosis, decreased PD-1 and LAG3 expression, and promoted immune response in sepsis. Conclusion: In conclusion, this study confirmed that downregulation of TCF7...
Gene SummaryThis gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. Th...