A: GESA analysis revealed that MACC1 was enriched in glycolytic signaling pathways; B: The correlation between MACC1 and glycolytic marker genes; C: Detect the cell viability of rectal cancer oxaliplatin resistant cells ...
SpecificityThe antibody detects endogenous levels of total TCF7 protein. Immunogen TypePeptide Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human transcription factor 7 (T-cell specific, HMG-box) ...
Single-cell analysisT cellsTCF1/TCF7Tertiary lymphoid structure/organOBJECTIVES :Despite substantial advances in treatment, clinical outcomes for oral squamous cell carcinoma (OSCC) remain unsatisfactory. Tumor-infiltrating lymphocytes (TILs) are an important prognostic factor for patients and are ...
在再喂养条件下,肝脏Tcf7l2缺乏显著上调了Srebf1c mRNA水平(图第7a段)。然而,TCF7L2不影响胰岛素、SREBP1c(自动调节)或LXR激动剂T0901317诱导的Srebf1c启动子活性(图7b)。因此,我们研究了TCF7L2是否调节可以在肝脏脂肪变性发...
CAR-T相关蛋白 免疫检查点蛋白 其他蛋白 ELISA试剂盒 ELISA抗体对 Human ELISA Kit Mouse ELISA Kit Rat ELISA Kit Other ELISA Kit 其他试剂 支原体检测试剂盒 飞克级超敏ECL液 预染彩虹蛋白Marker 定制服务 抗体定制服务 兔多抗制备 重组兔单抗制备
(8)TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiationImmunityJuly 1, 2023Andrea C. Pichler, Nadège Carrié, Marine Cuisinier, Samira Ghazali, Allison Voisin, Pierre-Paul Axisa, Marie Tosolini, Céline Mazzotti, Dominic P. Go...
The family of T-cell factor/lymphoid enhancer factors comprises four members: TCF7 (formerly called TCF1), TCF7L1 (TCF3),TCF7L2(TCF4) andLEF1[37]. In the absence of canonical WNT signals, these HMG-type TFs repress gene expression. Upon canonical WNT signaling, the transcriptional co-act...
(two-tailed ratio t-test, n = 3). (E) Western blot analysis shows no change in the expression of BAF170 in lncTCF7 knockdown cell lines (representative data from duplicate experiments). Normalized values are shown below the blot. (F) Co-immunoprecipitation showed the interaction between...
Wnt suppressor and stem cell regulator TCF7L1 is a sensitive immunohistochemical marker to differentiate testicular seminoma from non-seminomatous germ cel... The accurate classification and proper identification of testicular germ cell tumors is imperative for treatment selection and clinical prognosis. ...
Nuclear CTNNB1 interacts with a variety of proteins; the best characterized are the T cell factor/lymphoid enhancer factor (TCF/LEF) transcription factors. This family contains four members, each of which recognize and bind to a shared DNA motif (“Wnt-responsive elements,” or WREs) through...