TCA cycle metabolites have diverse non-metabolic signaling roles with important effects in physiology and disease. Metabolites such as acetyl-CoA, itaconate, succinate, fumarate, and L-2-HG can alter the response of both the innate and adaptive immune systems. Other functions like lymphangiogenesis ...
It is operational from 1.08 V to 3.6 V on both the A- side and B-side. This allows the device to interface between lower and higher logic signal levels at any of the typical 1.2-V, 1.8-V, 2.5-V, and 3.3-V supply rails. The OE input pin is referenced to VCCA, can be tied ...
Although anti-topo II drugs are efficacious, they also elicit cytotoxic side effects in normal cells; insights into how topo II is regulated in different cellular contexts is essential to improve their targeted use. Using chemical fractionation and mass spectrometry, we have discovered that topo II...
Some third parties are outside of the European Economic Area, with varying standards of data protection. See our privacy policy for more information on the use of your personal data. Manage preferences for further information and to change your choices. Accept all cookies ...
properly biasing the gate of the pass-FET, the FET can turn on (low RDSON), when either side input voltage drops to ~ 1 voltage threshold below the lowest of the two supplies. The TCA9416 is part of the TI "Switch" type voltage translator family and employs key circuits to enable ...
Therefore, this study aimed to investigate the antibacterial effects of IA and DI on bacterial growth, membrane integrity, motility, biofilm formation, and virulence. Additionally, the activities of ICL and SDH and their metabolites were quantified, together with untargeted metabolomics, to analyze the...
The preceding experiments strongly indicate the existence of a promoter element in the Tca2gag-poljunction region. However, they do not exclude the possibility that luciferase expression (and in Tca2 itself,polexpression) is being driven by composite effects, for example by a combination of stop ...
side and B-side. This allows the device to interface between lower and higher logic signal levels at any of the typical 1.2-V, 1.8-V, 2.5-V, and 3.3-V supply rails. The OE input pin is referenced to VCCA, can be tied directly to VCCA, but it is also 3.6-V tolerant. The...
properly biasing the gate of the pass-FET, the FET can turn on (low RDSON), when either side input voltage drops to ~ 1 voltage threshold below the lowest of the two supplies. The TCA9416 is part of the TI "Switch" type voltage translator family and employs key circuits to enable ...
marismortui was determined as 26 ± 5 mM, and the equilibrium of the preceding glutamate mutase reaction is not on the side of methylaspartate (Km = 0.093 at 30 °C) [55]. Indeed, the cytoplasmic glutamate concentration in the acetate-grown H. marismortui cells was 35 ± 5 mM (compared...