TBK1-IN-1 是一种具有特异性和高效性的 TANK 结合激酶 1 (TBK1) 抑制剂(IC50: 22.4 nM),具有抗癌活性。TBK1-IN-1 对 TBK1 下游靶基因 cxcl10 和 ifnβ 的表达有抑制作用。 规格价格库存数量 1 mg¥ 981现货 大包装 & 定制 实验操作小课堂 ...
英文名称 TBK1-IN-1 储存温度 -20°C储存 运输条件 超低温冰袋运输 产品介绍 TBK1-IN-1 is a potent and selective TANK binding kinase 1 (TBK1) inhibitor with an IC 50 value of 22.4 nM. TBK1-IN-1 inhibits TBK1 downstream target genes cxcl10 and ifnβ expression. TBK1-IN-1 has anticanc...
产品活性:TTBK1-IN-1 是一种强效、选择性、脑渗透型 tau 微管蛋白激酶 1 (TTBK1) 抑制剂,IC50 为2.7 nM。TTBK1-IN-1 可用于阿尔茨海默病及相关疾病的研究。 研究领域:Others 作用靶点:Others In Vitro: In primary mouse neuronal cultures at DIV14, and analysis of neurite branching is used as a ...
TBK1/IKKε-IN-1物理化学性质 分子量498.53 推荐供应商: 上海化源世纪贸易有限公司 上海市上海市普陀区 产品名:TBK1/IKKε-IN-1 纯度:98.0% 规格: 联系人:徐乾明 联系电话:13311869306 查看所有供应商和价格请点击: TBK1/IKKε-IN-1生产厂家 TBK1/IKKε-IN-1价格...
TBK1/IKKε-IN-1 是一种双重 TBK1 和 IKKε 抑制剂,IC50s 值 <100 nM。详细信息请参考专利文献 US20160376283 A1 中 Example 60 中的化合物 274。更多产品详情查看:www.medchemexpress.cn/Tbk-IKK_epsilon_-IN-1.html上一篇:CE3F4 | MedChemExpress (MCE) 下一篇:JT010 | MedChemExpress (MCE) AI...
TANK-binding kinase 1 (TBK1); inhibitor of |[kappa]|-light polypeptide gene enhanced in B cells kinase-|[epsi]| (IKBKE; IKK-i); HER2 (EGFR2; ErbB2; neu)In vitro and mouse studies suggest inhibiting TBK1 could help treat HER2 + breast cancers.Science-Business eXchange...
Nucleic acid sensing signaling pathways in THP1-Dual™ cells THP1-Dual™ KO-TBK1 cells were generated from theTHP1-Dual™ cell line, which is derived from the human THP-1 monocytes, through the stable knockout of the TBK1 gene. TBK1 (TANK-binding kinase 1) functions as a key node...
TBK1/IKKε-IN-4,CAS:1381930-17-1,TBK1/IKKε-IN-4 是一种 6-氨基吡唑并嘧啶衍生物,也是一种有效的,选择性的 TBK1 和 IKKε 抑制剂,IC50 值分别为 13 nM 和 59 nM。TBK1/IKKε-IN-4 对其他蛋白质激酶(包括 PDK1,PI3K 家族成员和 mTOR)的活性降低了 100-1000 倍。
Its two homologs, TTBK1 and TTBK2, show different expression patterns and different involvements in physiological mechanisms of great importance such as mitosis, ciliogenesis and neurotransmission. Their phosphorylation activity has also linked them to the development of neurodegenerative diseases like ...
英文名称: TBK1-IKKε inhibitor II 英文同义词: TBK1-IKKε inhibitor II;1H-Pyrazolo[3,4-d]pyrimidin-6-amine, N-[3,4-dimethoxy-5-[3-(4-methyl-1-piperazinyl)propoxy]phenyl]-1-(4-methoxyphenyl)-;TBK1/IKKε-IN-4;TBK1/IKKε-IN-4,TBK1-IKKε inhibitor II;TBK1/IKKε IN 4,TBK-1/IKKε...