Severe asthenia reported; symptoms of fatigue and weakness may last a few days up to several weeks and may be associated with deterioration of performance status in patients with progressive disease Based on findings from animal reproduction studies and its mechanism of action, can cause fetal harm...
How does docetaxel work (mechanism of action)? Docetaxel is a type of medicine known as chemotherapy. It works by stopping the ability of certain cells to divide, which prevents them from multiplying. This means it can slow or stop cancer tumors from growing. How is docetaxel supplied (dosa...
Docetaxel has a novel mechanism of action since it binds to tubulin inducing itsnpolymerization and promoting stable microtubule formation. Several differences exist between docetaxel andnpaclitaxel: (i) broader activity of docetaxel against freshly explanted human tumors than paclitaxel; (ii) a 2-n...
TAXOTERETaxol is a structurally complex natural plant product with a novel mechanism of action. The supply of this drug is limited by its low abundance ... CD Runowicz,PH Wiernik,AI Einzig,... - 《Cancer》 被引量: 289发表: 1993年 Paclitaxel (TaxolTM) and docetaxel (TaxotereTM): Not ...
关键词: Keywords Docetaxel TaxotereR RP 56976 antitumor efficacy mechanism of action resistance biodynamics toxicology DOI: 10.1097/00001813-199506000-00001 被引量: 732 年份: 1995 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 国家科技图书文献中心 (权威机构) 万方医学 dx.doi.org NCBI ...
Therefore our focus should indeed be on discovery of drugs of novel structure and/or mechanism of action. In the last few years, two new classes of drugs have received increasing attention, although their classification as 'new' is not completely correct. The first taxoid and the first ...
Paclitaxel (Taxol), the prototype of a new class of plant-derived antineoplastic compounds, is a natural product isolated from the Pacific yew. Docetaxel (Taxotere) is a hemisynthetic product derived from the European yew. These agents share a unique mechanism of cytotoxic action by promoting asse...
What Are Side Effects of Taxotere? Taxotere may cause serious side effects including: stomach pain or tenderness, diarrhea, fever, injection site pain, burning, irritation or skin changes, redness or peeling of the skin on your arms or legs, ...
What Are Side Effects of Taxotere? Taxotere may cause serious side effects including: stomach pain or tenderness, diarrhea, fever, injection site pain, burning, irritation or skin changes, redness or peeling of the skin on your arms or legs, ...
As if losing the hair from one’s head was not enough, the immune response mechanism of alopecia causes the loss of hair all over the body, including eyebrows, eyelashes, pubic hair, and underarm hair. This fact was never disclosed to the patients, so they never had the opportunity to ...