Special Section: Gene Expression and Development Tamar Juven-Gershon, James T. Kadonaga, in Developmental Biology, 2010 The TATA box is the first core promoter motif that was discovered (Goldberg, 1979) as well as the best known core promoter element. The metazoan TATA box consensus is TATAWA...
the use of shorter probes. For more information on MGB probes, please consult the following manual: "Primer Express v1.5 and TaqMan MGB Probes for Allelic Discrimination: All PCR Instruments: User Bulletin." You can find a copy on our website by entering this title in the main search box....
Applied Biosystems™ 人 TBP(TATA 盒结合蛋白)内源性对照品(FAM™ ⁄ MGB 探针,非限制性引物)适合用作内源性对照。与其他基因表达检测试剂盒配合使用时,可以对 cDNA 样品中的相对基因表达进行定量测定。探针用 6FAM™ 染料 - MGB 标记,引物为非限制性引物。可用于单重 PCR 反应。内源性对照品应与库存...
TATA box binding proteinGene expression is highly controlled and regulated in living cells. One of the first steps in gene transcription is recognition of the promoter site by the TATA box Binding Protein (TBP). TBP recruits other transcriptions factors and eventually the RNA polymerase II to ...
Gene expression is highly controlled and regulated in living cells. One of the first steps in gene transcription is recognition of the promoter site by the TATA box Binding Protein (TBP). TBP recruits other transcriptions factors and eventually the RNA polymerase II to transcribe the DNA in mRNA...
the others may be able to bind to non-TATA promoter regions. RNA polymerase is able to recognize the presence of transcription factors as a signal to bind to that location. After binding to the TATA box, RNA polymerase is at the initiation site and can now begin to transcribe the gene. ...
In addition to the TATA box, GC box and poly (A) tail, other gene expression-related elements composed of variant nucleotide sequences could also be targets of BBR in biological systems. Due to the limited cell-compartment distribution of BBR and the different binding affinities of BBR to ade...
Protein–protein interaction assays using purified proteins revealed that residues 124–220 of the EICP27 protein mediate its direct interaction with TATA box-binding protein (TBP). Partial deletion of this TBP-binding domain attenuated the ability of the EICP27 protein to stimulate the IE and ...
分析启动子区域内调控元件是阐明基因转录起始机制的重要前提.利用从PlanPromDB数据库下载的植物Pol-ⅡTATA和TATA-less启动子数据,深入分析了两类启动子GC偏好、位点结构保守性、序列碱基组分、保守模体分布、TATAbox位点分布及关联位点保守性等特点,统计出两类植物启动子许多特有的序列组分和结构规律,这些规律对进一步揭示...
TAF7L (TATA-Box Binding Protein Associated Factor 7 Like) is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor comp...