将各种原核基因同RNA聚合酶全酶结合后,用DNase I水解DNA,最后得到与RAN聚合酶结合而未被水解的DNA片段,这些片段有一个由5个核苷酸(TATAA)组成的共同序列,以其发现者的名字命名为Pribnow框(Pribnowbox),这个框的中央位于起点上游10bp处,所以又称—10序列(—10 sequence),后来在—35 bp处又找到...
Flatters D, Young M, Beveridge DL, Lavery R (1997). Conformational properties of the TATA- box binding sequence of DNA. J Biomol Struct Dyn 14: 757-65.Flatters, D., M. Young, D.L. Beveridge, and R. Lavery. 1997. Conformational properties of the TATA-box binding sequence of DNA. ...
The TATA-binding protein (TBP) initiates assembly of transcription preinitiation complexes on eukaryotic class II promoters, binding to and restructuring consensus and variant “TATA box” sequences. The sequence dependence of the DNA structure in TBP·TATA complexes has been investigated in solution ...
pribnowbox序列是指TATAAT。Pribnow框,原核生物中,在启动子上游有一个由5到6个核苷酸组成的共有序列,以其发现者的名字命名为Pribnow框(Pribnowbox)。中央位于起点上游10bp处,所以又称-10序列(-10sequence),是转录的解旋功能部位,具有高度保守性和一致性。Pribnow框盒(Pribnowbox)大肠杆菌基因组为4...
1.2 The TATA box and the amino acid residues involved in DNA binding The sequence elements in the core promoter serve as a platform for the assembly of transcription preinitiation complexes. The TATA box was the first element described in the core promoter. The motif consists of an A/T-rich...
TATA box指的是古菌和真核生物启动子区域里面的叫法,细菌中tata box的同系物被叫做pribnow box。两者功能类似但是pribnow box的序列相对较短,一般在-10 有6bp,在-35有8-12bp 其实
TATAWAW (w 代表 A或 T) ;GC.box 是转 录因子 SP1 所识别 的 DNA 序列 ,其序列格式为 GG~ GG;CAAT—box 是转录 因子 CBF 在 DNA 序列上的结合位点 ,其序列格式为 CCAAT 。 TATA —box 的模体识 别可 以通过在启动 子序列上是否发现 T A TAw A w 特征序 列实现 。同样 ,GC—box 和 ...
转基因CaMV35s启动子中一个包含TATA-box在内的19bp回文数列可能充当重组热点[1],一旦进入人体细胞的细胞核,则有可能利用细胞自身的双链修复机制[2]与人体基因组发生基因重组(入侵人类基因组,成为人体基因组的一分)。另外,CaMV35s启动子序列不同于一般DNA序列,其含有与CREB转录因子相结合的特异性序列,可以通过CREB...
pribnow序列正确的是TATAAT 不
The TATA box is a DNA element with the typical sequence of TATAAA (albeit many variations exist). It is found in the core promoter region of some but...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your...