TAT-modified tetramethylpyrazine-loaded nanoparticles for targeted treatment of spinal cord injuryJian Li a cJun Wei aYujie Wan aXingjie Du aXiaosheng Bai aChunhong Li aYan Lin aZhongbing Liu aMeiling Zhou bZhirong Zhong aJournal of Controlled Release...
HIV-1 transcription activator protein Tat is phosphorylated in vitro by CDK2 and DNA-PK on Ser-16 residue and by PKR on Tat Ser-46 residue. Here we analyzed Tat phosphorylation in cultured cells and its functionality. Mass spectrometry analysis showed pr
Li, HongD. Wade, JohnLambert, PaulKumar, AjitKashanchi, FatahCurrent HIV ResearchPumfery, A., L. Deng, A. Maddukuri, C. de la Fuente, H. Li, J. D. Wade, P. Lambert, A. Kumar and F. Kashanchi (2003). "Chromatin remodeling and modification during HIV-1 Tat-activated ...
Furthermore, when utilizing an in vitro transcription assay, as well as a Tat mutant virus, we found that ectopic expression of only wild-type Tat in the presence of p300, and not a lysine 41 Tat mutant, could activate HIV-1 chromatin DNA, as evidenced by the absence of HIV-1 virion ...