COVID-19HAPLOTYPESCROSS-sectional methodSYMPTOMSCOVID-19 pandemicThe TAS2R38 gene is well known for its function in bitter taste sensitivity, but evidence also suggests a role in innate immunity. TAS2R38 may be relevant in coronavirus disease 2019 (COVID-19), but...
ASSOCIATION OF THE TAS2R38 GENE POLYMORPHISM WITH THE SENSITIVITY OF GUSTATORY AND OLFACTORY FUNCTION TO SARS-CoV2 INFECTIONIvona, KenjiNaida, Lojo-KadriBelmina, ari MediNikolina, TomiJasmin, RamiLejla, PojskiGenetics & Applications
6‐ n ‐propylthiouracil taste perception is mediated by the TAS2R38 receptor, and reduced 6‐ n ‐propylthiouracil sensitivity has been associated with several diseases not typically related to taste function. Objectives: We evaluated the 6‐ n ‐propylthiouracil taste perception and the TAS2R38 ...
All subjects received standardized tests for smell and taste function and were genotyped for the TAS2R38 gene.Results: PAV/PAV homozygous patients gave high PTC ratings, whereas PAV/AVI genotypes reported lower values, which are similar to those determined in AVI/AVI or rare ge...
Real-time polymerase chain reaction (qRT-PCR) was performed in duplicates using TaqManTM Fast Advanced Master Mix (Applied Biosystem, Thermofisher, Waltham, MA, USA; cat No 4444556) and TaqManTM Gene expression assays for the TAS2R38 gene (Applied Biosystem Hs00604294_s1, Thermofisher, Waltham...
The TAS2R38 gene is one of the most studied genes in the TAS2R gene family. TAS2R38 encodes a seven transmembrane G protein-coupled receptor [9] binding to the thiourea group present both in synthetic compounds (e.g., phenylthiocarbamide (PTC); 6-n-propylthiouracil (PROP)) and also ...