Targeted Therapy for Malignant Brain TumorsTargeted Therapy for Malignant Brain TumorsTemozolomide resistanceAntiangiogenesisAnti-EGFRVirotherapiesmicroRNA-based strategiesGlioblastoma multiforme (GBM) is the most aggressive human brain tumor. Standard of care includes surgical resection, radiation therapy, and co...
There are various traditional treatments of brain tumor, including radiation therapy, surgery, and chemotherapy, but there are lots of side effects and disadvantages associated with the conventional therapies. As a result, this chapter reviews the current status, causes, diagnosis of brain tumor, ...
Radiation can cause tumor cells to release chemokines and growth factors, such as CCL2, CCL7, and CSF-1, that are important for MDSC recruitment in the TME. The nonreceptor tyrosine kinase ABL1 is activated by radiation before it translocates to the promoter region of CSF-1 and promotes th...
Gliomas are the most common primary malignant brain tumour [1]. The current standard of care for gliomas includes a combination of surgery, chemotherapy, and radiation therapy, depending on the specific type of tumour. However, even with current treatments, the median survival times for patients ...
VEGF-targeted therapy has multiple mechanisms of action that might be dependent on tumour type. VEGF-targeted therapy affects vascular function (flow and permeability) in addition to blocking further new blood vessel growth. Abstract Several vascular endothelial growth factor (VEGF)-targeted agents, adm...
radiation therapystereotactic radiosurgerychemotherapyPURPOSE OF REVIEW: Melanoma is the third most common metastatic brain tumor in the United States and is a... AA Tarhini,SS Agarwala - 《Current Opinion in Oncology》 被引量: 172发表: 2004年 ...
X-ray diffraction (XRD) patterns were performed using MiniFlex600 Focus diffractometer (Rigaku) under Cu Kα radiation (parameters: 600 W). Fourier transform infrared (FTIR) spectra were acquired from Thermo Nicolet NEXUS 470 spectrometer. ICP-MS was detected by an Analytik Jena inductively ...
Head and neck squamous cell carcinoma (HNSCC) is treated primarily through a combination of surgery and radiation therapy. The problem of radioresistance, however, persists and requires new approaches to overcome it. Tumor hypoxia has be... PH Boasquevisque,V Schoeneberger,L Caporiccio,... - ...
Recent advances in neoantigen research have accelerated the development and regulatory approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and antibody-based therapies, especially for solid tumors. Neoantigens are newly fo
especially in patients who have been heavily pretreated with radiation and chemotherapy.337The development of allogeneic “universal” CAR-T products aims to address these challenges. The technology has the potential to turn CAR-T cells into “off-the-shelf” drugs, with the advantages of large-sc...