Therefore, providing sufficient oxygen in tumor area may be beneficial for radiation therapy. To study the potential role of such strategy for brain tumor treatment, we used focused ultrasound to treat brain tumor bearing animals before radiation therapy. As compared with non-ultrasound treatment ...
Resection of brain tumors is followed by chemotherapy and radiation to ablate remaining malignant cell populations. Targeting these populations stands to r... TD Azad,J Pan,ID Connolly,... - 《Neurosurgical Focus》 被引量: 26发表: 2015年 Therapeutic strategies to improve drug delivery across the...
1991 Treatment of malignant brain tumors with focused ultrasound hyperthermia and radiation: results of a phase I trial Clinical Yu T, Wang G, Hu K, Ma P, Bai J, Wang Z 2004 A microbubble agent improves the therapeutic efficiency of high intensity focused ultrasound: a rabbit kidney study Pr...
Bacteria-based tumor therapy has recently attracted wide attentions due to its unique capability in targeting tumors and preferentially colonizing the core area of the tumor. Various therapeutic genes are also harbored into these engineering bacteria to
Lozano, in Brain Mapping, 2015 Focused Ultrasound High-intensity focused ultrasound was developed in the 1940s and has most often been used as a treatment for benign and malignant tumors including pancreas, liver, prostate, and breast carcinomas, soft tissue sarcomas, and uterine fibroids (Napoli...
a brain tumor." Arvanitis, an assistant professor at Georgia Institute of Technology, worked on this study at both the Edwin L. Steele Laboratories for Tumor Biology in the MGH Department of Radiation Oncology and in his new Biomedical Acoustics and Image-Guided Therapy laboratory at Georgia T...
for the use of therapeutic ultrasound in preclinical investigation, such as neuroprotectant delivery for ischemia-reperfusion brain injuries3, antibody delivery for treatment of Alzheimer's disease4, gene delivery for Huntington's and Parkinson's diseases5,6, and chemotherapeutics for brain tumors7–10...
Nazeri said tauopathies such as Alzheimer's disease are similar to brain tumors. "While brain tumor behavior and treatment response are dictated by the specific mutations they harbor, the tau protein shows great heterogeneity in the pattern of phosphorylation as well as other post-translational modif...
Researchers and clinicians have been working to use focused ultrasound combined with microbubbles to open the blood-brain barrier (BBB) for both noninvasive diagnostic use as well as to deliver treatments to the brain for tumors and neurodegenerative diseases. However, the few existing devices for ...
FUS has been explored as a method to deliver therapies across the BBB for malignancies13, neurodegenerative diseases14,15, and movement disorders15,16,17. The technology has also been shown to be safe and efficacious in patients with Alzheimer’s Disease and brain tumors18,19. The safety and ...