Target-decoy search strategy for mass spectrometry-based proteomics. Methods Mol Biol. 2010;604:55-71.Elias JE, Gygi SP. Target-decoy search strategy for mass spectrometry-based proteomics. Proteome Bioinformatics. 2010:55-71.Elias J E, Gygi S P. Target-decoy search strategy for mass ...
这个decoy应该怎么翻译呀？
The target-decoy search strategy represents a straightforward and effective way to manage this effort. Despite the apparent simplicity of this method, some controversy surrounds its successful application. Here we clarify our preferred methodology by addressing four issues based on observed decoy hit ...
An averaging strategy to reduce variability in target-decoy estimates of false discovery rateDecoy database search with target-decoy competition (TDC) provides an intuitive, easy-to-implement method for estimating the false discovery rate (... U Keich,K Tamura,WS Noble 被引量: 0发表: 2018年 ...
Balgley et al., 2007 [2] compared the performances of four popular search tools using TDA, noting that "the target-decoy search strategy permits an impartial initial assessment of search results." We argue that the assumption that TDA can be used with any MS/MS database search tool is ...
Target-decoy search, Target-small decoy search, False discovery rateBackgroundOne of the most important steps in peptide identification is to estimate the false discovery rate (FDR). The most commonly used method for estimating FDR is the target-decoy search strategy (TDS). While this method is...
Perspective target decoy peptide search strategy large scale MS protein identify in proteomeGygi, S P
The target-decoy search strategy has been successfully applied in shotgun proteomics for validating peptide and protein identifications. If, on one hand, this method has proven to be very efficient for error estimation, on the other hand, little attention has been paid to the resulting sensitivity...
Jiang X,Han G,Feng S, et al.Automatic validation of phosphopeptide identifications by the MS2/MS3 target-decoy search strategy. Journal of Proteome Research . 2008Jiang, X. N.; Han, G. H.; Feng, S.; Jiang, X. G.; Ye, M. L.; Yao, X. B.; Zou, H. F. Automatic Validation ...
The target/decoy search strategy represents a simple way to make this challenge manageable. Despite the apparent simplicity of this method, some amount of controversy surrounds its successful application. Here, we clarify our preferred methodology, and suggest several ways this powerful technique can ...